664372-19-4

Basic information

• Product Name: 2-Propen-1-one, 1-(3-bromo-2-thienyl)-3-(4-methoxyphenyl)-, (2E)-
• CAS NO: 664372-19-4
• Molecular Formula: C14H11BrO2S
• Molecular Weight: 323.21
• Mol File: 664372-19-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-Propen-1-one, 1-(3-bromo-2-thienyl)-3-(4-methoxyphenyl)-, (2E)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propen-1-one, 1-(3-bromo-2-thienyl)-3-(4-methoxyphenyl)-, (2E)-(664372-19-4)
• EPA Substance Registry System: 2-Propen-1-one, 1-(3-bromo-2-thienyl)-3-(4-methoxyphenyl)-, (2E)-(664372-19-4)

Safety Data

• Hazardous Substances Data: 664372-19-4(Hazardous Substances Data)

Upstream product

• 42877-08-7 1-(3-bromothiophen-2-yl)ethanone 
• 123-11-5 4-methoxy-benzaldehyde 

Downstream Products

• 869370-83-2 5-(3-bromo-2-thienyl)-2-cyano-3-(4-methoxyphenyl)-5-oxovaleronitrile 

Relevant articles and documents

Reactions of heteroaryl substituted propenones

Thienyl- and furylpropenones reacted with malonates, cyanoacetates, and malononitrile giving addition products which could be cyclized to heteroaryl substituted dihydropyranes, cyclohexanols, and piperidones. Heteroaryl substituted cyclopropyl ketones were prepared by reactions with Me 3SO+ I-, and by reaction with Lewis acids they were transformed into substituted dihydrobenzo[b]furanone or -thiophenone, or γ-hydroxy ketones. Cycloadditions with thiophene derivatives allowed the synthesis of substituted benzo[b]thiophene derivatives, but with poor yields. Structures and stereochemistry were established mainly by means of NMR spectroscopy. Springer-Verlag 2005.