6648-30-2Relevant articles and documents
Synthetic method of alpha-position dibromination of alpha-heterocyclic carbonyl compound
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Paragraph 0027-0028; 0063-0065, (2020/05/30)
The invention discloses a synthetic method of alpha-position dibromination of an alpha-heterocyclic carbonyl compound, and belongs to the technical field of organic synthesis, and the method comprisesthe following steps: by taking the alpha-heterocyclic carbonyl compound as a raw material, adding a bromination reagent, a solvent and a small molecular catalyst, and reacting under light irradiationto obtain a corresponding product. The method has the advantages of high yield, simplicity and convenience in operation, mild reaction conditions, wide substrate adaptability and the like.
Trihaloisocyanuric acids as convenient reagents for regioselective halogenation of β-dicarbonyl compounds
Mendon?a, Gabriela F.,Sindra, Haryadylla C.,de Almeida, Leonardo S.,Esteves, Pierre M.,de Mattos, Marcio C.S.
scheme or table, p. 473 - 475 (2009/05/07)
The reaction of β-dicarbonyl compounds (β-ketoesters and β-diketones) with 0.34 mol equiv of trichloro- and tribromoisocyanuric acids produced regioselectively the corresponding α-monohalo β-dicarbonyl compound. On the other hand, utilization of 0.68 mol equiv of the trihaloisocyanuric acid produced the α,α-dihalo β-dicarbonyl compound.
