66488-79-7

Basic information

• Product Name: 4-ISOBUTOXY-3-METHOXYBENZALDEHYDE
• Synonyms: CHEMBRDG-BB 4302404;4-ISOBUTOXY-3-METHOXYBENZALDEHYDE;AKOS BC-3061;AKOS BBS-00006528;AKOS B000269;4-isobutoxy-3-methoxybenzaldehyde(SALTDATA: FREE);3-methoxy-4-(2-methylpropoxy)benzaldehyde
• CAS NO: 66488-79-7
• Molecular Formula: C₁₂H₁₆O₃
• Molecular Weight: 208.25
• Mol File: 66488-79-7.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 313.5 °C at 760 mmHg
• Flash Point: 134.4 °C
• Appearance: /
• Density: 1.046 g/cm³
• Vapor Pressure: 0.000495mmHg at 25°C
• Refractive Index: 1.517
• CAS DataBase Reference: 4-ISOBUTOXY-3-METHOXYBENZALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-ISOBUTOXY-3-METHOXYBENZALDEHYDE(66488-79-7)
• EPA Substance Registry System: 4-ISOBUTOXY-3-METHOXYBENZALDEHYDE(66488-79-7)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 66488-79-7(Hazardous Substances Data)

Usage

General Description

4-ISOBUTOXY-3-METHOXYBENZALDEHYDE is a chemical compound with the molecular formula C12H16O2. It is a benzaldehyde derivative that contains both an isobutoxy and a methoxy group. 4-ISOBUTOXY-3-METHOXYBENZALDEHYDE is often used as a fragrance ingredient in various consumer products, such as perfumes, soaps, and cosmetics. It has a sweet, floral odor and is commonly derived from natural sources such as plants and fruits. Additionally, 4-ISOBUTOXY-3-METHOXYBENZALDEHYDE is used in the production of flavorings and as a precursor in organic synthesis. However, it is important to handle this chemical with care, as it can be irritating to the skin, eyes, and respiratory system.

InChI:InChI=1/C12H16O3/c1-9(2)8-15-11-5-4-10(7-13)6-12(11)14-3/h4-7,9H,8H2,1-3H3

Upstream product

• 78-77-3 Isobutyl bromide 
• 121-33-5 vanillin 
• 513-36-0 isobutyryl chloride 

Downstream Products

• 3535-35-1 4-isobutoxy-3-methoxy benzoic acid 
• 66488-82-2 4-(4-isobutoxy-3-methoxy-benzylidene)-2-phenyl-4H-oxazol-5-one 
• 744243-58-1 (E)-3-(4-isobutoxy-3-methoxyphenyl)acrylic acid 
• 902745-25-9 3-amino-3-(4-isobutoxy-3-methoxy-phenyl)-propionic acid 
• 1383744-30-6 N-(tert-butyloxycarbonyl)-N'-(4-(2-methylpropyloxy)-3-methoxy-benzyl)piperazine 

Relevant articles and documents

Potent human dihydroorotate dehydrogenase inhibitory activity of new quinoline-4-carboxylic acids derived from phenolic aldehydes: Synthesis, cytotoxicity, lipophilicity and molecular docking studies

A series of novel 2-substituted quinoline-4-carboxylic acids was synthesized by Doebner reaction starting from freely available protocatechuic aldehyde and vanillin precursors. Human dihydroorotate dehydrogenase (hDHODH) was recognised as a clear molecular target for these heterocycles. All compounds were also tested for their antiproliferative potential against three cancer cells (MCF-7, A549, A375) and one normal cell line (HaCaT) to evaluate the selective cytotoxicity. Quinoline derivatives 3f and 3g were identified as potent hDHODH inhibitors while 3k and 3l demonstrated high cytotoxic activity against MCF-7 and A375 cells and good selectivity. In addition, the logD7.4 values obtained by the experimental method were found to be in the range from ?1.15 to 1.69. The chemical structures of all compounds were confirmed by IR, NMR and elemental analysis. The compounds pharmacology on the molecular level was revealed by means of molecular docking, highlighting the structural differences that distinguish highly active from medium and low active hDHODH inhibitors.

N,N+hu 1 +l SUBSTITUTED PIPERAZINES HAVING COMBINED ANTIAGGREGANT, ANTICOAGULANT AND VASODILATORY ACTIVITY, AND METHOD FOR PRODUCING SAME

The invention relates to derivatives of N,N′-substituted piperazines of the general formula (I): where R1 and R2 denote linear or branched (C1-C4)alkyl, linear or branched (C1-C4)alkoxy, CH