664982-01-8Relevant articles and documents
Sequentially Catalyzed Three-Component Masuda-Suzuki-Sonogashira Synthesis of Fluorescent 2-Alkynyl-4-(7-azaindol-3-yl)pyrimidines: Three Palladium-Catalyzed Processes in a One-Pot Fashion
Drieβen, Daniel,Biesen, Lukas,Müller, Thomas J. J.
, p. 491 - 496 (2021)
The Masuda-Suzuki-Sonogashira sequence efficiently unites, in a one-pot fashion, a borylation, an arylation, and an alkynylation in the sense of a sequentially Pd-catalyzed three-component reaction to give fluorescent 2-alkynyl-4-(7-azaindol-3-yl) pyrimid
Enantioselective Synthesis of Cyclohepta[ b]indoles via Pd-Catalyzed Cyclopropane C(sp3)-H Activation as a Key Step
H?fner, Maximilian,Sokolenko, Yevhenii M.,Gamerdinger, Paul,Stempel, Erik,Gaich, Tanja
supporting information, p. 7370 - 7374 (2019/10/08)
An enantioselective synthesis of functionalized cyclohepta[b]indoles via Pd-catalyzed cyclopropane C-H activation followed by olefination and indole-vinylcyclopropane rearrangement is reported. The design of the chiral cyclopropane precursor was such that both enantiomeric cyclohepta[b]indoles were accessed from a single compound exhibiting a "hidden" symmetry plane. The scope of the method was demonstrated by varying the substituents on the cyclopropane as well as on the heterocycle itself.
Domino C-H functionalization reactions of gem-dibromoolefins: Synthesis of N-fused benzo[c]carbazoles
Huang, Richard Y.,Franke, Patrick T.,Nicolaus, Norman,Lautens, Mark
supporting information, p. 4395 - 4402 (2013/06/27)
A palladium-catalyzed domino transformation of gem-dibromoolefins leading to novel polycyclic benzo[c]carbazoles is described. A unique feature of the current reaction is the participation of both bromides in C-H functionalization processes. Mechanistic studies were conducted to ascertain the sequence of reaction events, and the results indicate that the (Z)-bromide likely reacts in preference to the (E)-bromide.