665000-76-0

Basic information

• Product Name: 2-amino-4-(2-chlorophenyl)-6-(hydroxymethyl)-8-oxo-4,8-dihydropyrano[3,2-b]pyran-3-carbonitrile
• Synonyms: 2-amino-4-(2-chlorophenyl)-6-(hydroxymethyl)-8-oxo-4,8-dihydropyrano[3,2-b]pyran-3-carbonitrile
• CAS NO: 665000-76-0
• Molecular Formula: C₁₆H₁₁ClN₂O₄
• Molecular Weight: 330.72254
• Mol File: 665000-76-0.mol
• Article Data: 13

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-amino-4-(2-chlorophenyl)-6-(hydroxymethyl)-8-oxo-4,8-dihydropyrano[3,2-b]pyran-3-carbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 2-amino-4-(2-chlorophenyl)-6-(hydroxymethyl)-8-oxo-4,8-dihydropyrano[3,2-b]pyran-3-carbonitrile(665000-76-0)
• EPA Substance Registry System: 2-amino-4-(2-chlorophenyl)-6-(hydroxymethyl)-8-oxo-4,8-dihydropyrano[3,2-b]pyran-3-carbonitrile(665000-76-0)

Safety Data

• Hazardous Substances Data: 665000-76-0(Hazardous Substances Data)

Upstream product

• 501-30-4 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one 
• 89-98-5 2-chloro-benzaldehyde 
• 109-77-3 malononitrile 
• 2698-41-1 o-chlorobenzylidene malononitrile 

Relevant articles and documents

Acetic Acid-Mediated Synthesis of Kojic Acid Derivatives

Abstract: A green acetic acid-mediated synthesis of kojic acid derivatives through amulticomponent reaction (MCR) has been developed. This new protocol is simpleand efficient; it involves a one-pot reaction of equimolar amounts of kojicacid, aromatic alde

One-pot synthesis of 2-amino-4,8-dihydropyrano[3,2-b]pyranes and pyridopyrimidines under mild conditions

1,8-Diazabicyclo[5.4.0]undec-7-ene immobilized on silica (SB-DBU)Cl as a reusable and heterogeneous catalyst was applied for the one-pot, three-component synthesis of 2-amino-4,8-dihydropyrano[3,2-b]pyrane-3-carbonitriles and pyridopyrimidines, under solvent-free conditions. The reaction was carried out at room temperature, and pure products were obtained in high yields and short reaction times (3–7 min). This work introduced an environmentally benign procedure for the synthesis of these classes of biological active compounds.

Ferrocene-containing ionic liquid supported on silica nanospheres (SiO2@Imid-Cl@Fc) as a mild and efficient heterogeneous catalyst for the synthesis of pyrano[3,2-b]pyran derivatives under ultrasound irradiation

A novel heterogeneous silica nanosphere-supported ferrocene-containing ionic liquid catalyst (SiO2@Imid-Cl@Fc) was designed and synthesised and was systematically characterised by Fourier transform infrared (FTIR) spectroscopy, field emission s