66508-11-0 Usage
Description
3-(N-Hydroxyamino)propyl Phosphonate, with the chemical abstracts service number 66508-11-0, is a synthetic compound that plays a significant role in various organic synthesis processes. It is characterized by its unique molecular structure, which includes a phosphonate group attached to a propyl chain with a hydroxyamino group. This structure endows it with versatile reactivity and compatibility with a range of chemical reactions, making it a valuable intermediate in the synthesis of more complex organic molecules.
Uses
Used in Organic Synthesis:
3-(N-Hydroxyamino)propyl Phosphonate is used as a key intermediate in organic synthesis for its ability to participate in a variety of chemical reactions. Its presence in a molecule can facilitate the formation of new bonds and the transformation of other functional groups, which is crucial in the development of pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 3-(N-Hydroxyamino)propyl Phosphonate is used as a building block for the synthesis of drug candidates. Its unique reactivity allows for the creation of novel molecular scaffolds that can exhibit specific biological activities, potentially leading to the discovery of new therapeutic agents.
Used in Agrochemical Development:
3-(N-Hydroxyamino)propyl Phosphonate also finds application in the agrochemical sector, where it is utilized in the synthesis of new pesticides and herbicides. Its versatility in organic synthesis enables the development of compounds with improved efficacy and selectivity against target pests and weeds.
Used in Specialty Chemicals Production:
Beyond the pharmaceutical and agrochemical industries, 3-(N-Hydroxyamino)propyl Phosphonate is also employed in the production of specialty chemicals. These can include materials for coatings, adhesives, and other industrial applications where unique chemical properties are required.
Check Digit Verification of cas no
The CAS Registry Mumber 66508-11-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,6,5,0 and 8 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 66508-11:
(7*6)+(6*6)+(5*5)+(4*0)+(3*8)+(2*1)+(1*1)=130
130 % 10 = 0
So 66508-11-0 is a valid CAS Registry Number.
InChI:InChI=1/C3H10NO4P/c5-4-2-1-3-9(6,7)8/h4-5H,1-3H2,(H2,6,7,8)
66508-11-0Relevant articles and documents
Regioselective palladium(0) catalyzed amination of carbonates of allylic α-hydroxyphosphonates with hydroxylamine derivatives: A convenient route to phosphonic acids related to the antibiotic fosmidomycin
Ohler,Kanzler
, p. 539 - 543 (1995)
Palladium(0) catalyzed amination of diisopropyl (1-methoxycarbonyloxy-2-propenyl)phosphonate (1) with tert-butyl (tert-butoxycarbonyloxy)carbamate (BocNHOBoc, 2a), and (N-acetyloxy)acetamide (AcNHOAc, 2b) proceeds regiospecifically and with high (E)-stereoselectivity to give the protected [3-(N-hydroxyamino)-1-propenyl]phosphonates 3a and 3b, respectively, in high yields. Hydrogenation of compounds 3a and 3b affords the corresponding propylphosphonates 4. Compounds 3a,b and 4a,b are further converted to precursors and analogues of the phosphonic acid antibiotic fosmidomycin.
Use of organophosphorus compounds for the therapeutic and prophylactic treatment of infections
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Page column 14, (2010/02/05)
Use of organophosphorus compounds of general Formula (I) for the therapeutic and prophylactic treatment of infections in humans and animals caused by viruses, fungi and parasites.
Studies on phosphonic acid antibiotics. III. Structure and synthesis of 3-(N-acetyl-N-hydroxyamino)propylphosphonic acid (FR-900098) and 3-(N-acetyl-N-hydroxyamino)-2(R)-hydroxypropylphosphonic acid (FR-33289)
Hemmi,Takeno,Hashimoto,Kamiya
, p. 646 - 650 (2007/10/02)
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