66521-34-4

Basic information

• Product Name: 2-[5-(benzyloxy)-1H-indol-3-yl]-N,N-dimethyl-2-oxoacetamide
• CAS NO: 66521-34-4
• Molecular Formula: C₁₉H₁₈N₂O₃
• Molecular Weight: 322.3578
• Mol File: 66521-34-4.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 527.6°C at 760 mmHg
• Flash Point: 272.9°C
• Density: 1.261g/cm³
• Vapor Pressure: 3.21E-11mmHg at 25°C
• Refractive Index: 1.646
• CAS DataBase Reference: 2-[5-(benzyloxy)-1H-indol-3-yl]-N,N-dimethyl-2-oxoacetamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[5-(benzyloxy)-1H-indol-3-yl]-N,N-dimethyl-2-oxoacetamide(66521-34-4)
• EPA Substance Registry System: 2-[5-(benzyloxy)-1H-indol-3-yl]-N,N-dimethyl-2-oxoacetamide(66521-34-4)

Safety Data

• Hazardous Substances Data: 66521-34-4(Hazardous Substances Data)

Usage

Molecular Structure

Indole ring
Benzyl ether group
Dimethylamide functional group
Ketone functional group

Potential Therapeutic Properties

Used in medicinal chemistry and pharmaceutical research
Potential inhibitor or modulator of biological processes

Applications

Medicinal chemistry
Pharmaceutical research

Ongoing Research

Further exploration of specific uses and applications
Investigation into its therapeutic potential in various medical contexts

Upstream product

• 22424-61-9 2-[5-(benzyloxy)-1H-indol-3-yl]-2-oxoacetyl chloride 
• 124-40-3 dimethyl amine 
• 506-59-2 N,N-dimethylammonium chloride 
• 79-37-8 oxalyl dichloride 
• 1215-59-4 5-benzyloxy-1H-indole 

Downstream Products

• 25390-67-4 5-Benzyloxy DMT 
• 487-93-4 bufotenin 
• 5787-02-0 5-hydroxy-N,N-dimethyltryptamine iodomethylate 
• 112626-00-3 [2-(5-benzyloxy-indol-3-yl)-ethyl]-trimethyl-ammonium; iodide 

Relevant articles and documents

Synthesis method of bufotenin and quaternary ammonium salt thereof and application in preparation of analgesic and anti-inflammatory drugs

The invention relates to a synthesis method of bufotenin and quaternary ammonium salt thereof. The method has the characteristics of simple steps, safe and convenient operation, high reaction efficiency, easy purification and separation, mild conditions a

Indole and indoline derivatives as 5-HT6 selective ligands

Three classes of indole and indoline derivatives are disclosed as ligands selective for the 5-HT6receptors, and hence of value in the treatment or prevention of CNS disorders, including Alzheimer's disease, Parkinson's disease, schizophrenia, depression and anxiety. A particular class, 1-substituted-4-(ω-N,N-dialkyl-aminoalkyl)indoles, are claimed as novel compounds.