66521-58-2 Usage
Description
(Z)-3-((dimethylamino)methylene)-1-methylpiperidin-4-one, also known as DMAMe-1-piperidin-4-one, is a psychoactive piperidine derivative with the molecular formula C10H18N2O. It is recognized for its stimulant effects on the central nervous system, which can lead to increased energy, alertness, and concentration. However, its use is associated with potential adverse effects such as increased heart rate, elevated blood pressure, and addiction.
Uses
Used in Recreational Drug Industry:
(Z)-3-((dimethylamino)methylene)-1-methylpiperidin-4-one is used as a recreational drug for its stimulant effects, which can enhance energy, alertness, and concentration. However, its use is controversial due to the associated health risks and potential for addiction.
Used in Illicit Substances:
(Z)-3-((dimethylamino)methylene)-1-methylpiperidin-4-one is also found in various illicit substances, contributing to their psychoactive effects. Due to its potential for abuse and the health risks involved, it has been listed as a controlled substance in some countries to regulate its distribution and use.
Check Digit Verification of cas no
The CAS Registry Mumber 66521-58-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,6,5,2 and 1 respectively; the second part has 2 digits, 5 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 66521-58:
(7*6)+(6*6)+(5*5)+(4*2)+(3*1)+(2*5)+(1*8)=132
132 % 10 = 2
So 66521-58-2 is a valid CAS Registry Number.
66521-58-2Relevant articles and documents
Selective α-Methylation of Ketones
Frolov, Andriy I.,Ostapchuk, Eugeniy N.,Pashenko, Alexander E.,Chuchvera, Yaroslav O.,Rusanov, Eduard B.,Volochnyuk, Dmitriy M.,Ryabukhin, Sergey V.
, p. 7333 - 7346 (2021/06/28)
The convenient and scalable preparative approach for the two-step α-methylation of ketones is described. The optimized protocols for regioselective preparation of enaminones with further diastereoselective and functional groups tolerant hydrogenation to α-methylketones are developed. The scope and limitations of the proposed methodology are discussed. The advantages compared to known procedures are demonstrated. The unexpected role of acetone in the hydrogenation is suggested. The evaluation of the method for both early building block synthesis and late-stage CH-functionalization is shown. The elaborate procedures' preparability and scalability are demonstrated by the synthesis of several α-methyl ketones up to 100 g amount.
