6653-42-5 Usage
Description
5-METHYL-1H-IMIDAZOL-2-YLAMINE, also known as 2-Amino-4-methylimidazole, is an organic compound with the chemical formula C4H6N4. It is a heterocyclic amine that serves as a key intermediate in the synthesis of various pharmaceutical compounds. Its molecular structure features a five-membered imidazole ring with a methyl group at the 5-position and an amino group at the 2-position.
Uses
Used in Pharmaceutical Synthesis:
5-METHYL-1H-IMIDAZOL-2-YLAMINE is used as a reagent in the synthesis of 1H-pyrrolo[2,3-c]pyridine-7-carboxamides, which are novel allosteric mGluR5 antagonists. These antagonists have potential applications in the treatment of neurological disorders, such as schizophrenia and Fragile X syndrome, by modulating the activity of the metabotropic glutamate receptor 5 (mGluR5).
Additionally, 5-METHYL-1H-IMIDAZOL-2-YLAMINE is used as a reagent in the synthesis of imidazo[1,2-a]pyrimidin-5(1H)-ones. These compounds are beta isoform selective phosphatidylinositol 3-kinase (PI3K) inhibitors, which play a crucial role in the regulation of cellular processes, such as cell growth, survival, and metabolism. Inhibition of PI3K beta isoform has been implicated in the treatment of various cancers and inflammatory diseases by targeting the PI3K/Akt/mTOR signaling pathway.
Check Digit Verification of cas no
The CAS Registry Mumber 6653-42-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,6,5 and 3 respectively; the second part has 2 digits, 4 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 6653-42:
(6*6)+(5*6)+(4*5)+(3*3)+(2*4)+(1*2)=105
105 % 10 = 5
So 6653-42-5 is a valid CAS Registry Number.
InChI:InChI=1/C4H7N3/c1-3-2-6-4(5)7-3/h2H,1H3,(H3,5,6,7)
