66608-11-5 Usage
Description
6-Chloronicotinoyl chloride, with the chemical formula C12H6Cl2N2O, is an organic compound that serves as an important intermediate in the synthesis of various pharmaceuticals and agrochemicals. It is a white to off-white crystalline solid that undergoes esterification reactions with diethylene glycol and pentaethylene glycol.
Uses
Used in Pharmaceutical Industry:
6-Chloronicotinoyl chloride is used as a key intermediate for the synthesis of various pharmaceutical compounds. It plays a crucial role in the development of new drugs and therapies.
Used in Agrochemical Industry:
6-Chloronicotinoyl chloride is used as a starting material for the synthesis of various agrochemicals, specifically insecticides. It contributes to the development of effective pest control solutions for agriculture.
Specific Applications:
1. 6-Chloronicotinoyl chloride is used as a synthetic intermediate for the production of [3H]imidacloprid, a candidate radioligand for studying the binding and action of imidacloprid, a widely used insecticide.
2. It is also used as a synthetic intermediate for the production of [3H]acetamiprid, another insecticide that is effective against various pests in agriculture.
3. 6-CHLORONICOTINOYL CHLORIDE 97 is used as a synthetic intermediate for the synthesis of N,N′-(1,4-phenylene)bis(6-(4-aminophenoxy) nicotinamide), a compound with potential applications in the pharmaceutical industry.
4. Additionally, 6-chloronicotinoyl chloride is used in the synthesis of 3-acetyl-6-chloropyridine, which can be further utilized in the development of various pharmaceutical compounds.
5. Lastly, it is used as a synthetic intermediate for the production of 1,3-dipropyl-8(6-chloro-3-pyridyl)xanthine, a compound with potential applications in the pharmaceutical industry.
Check Digit Verification of cas no
The CAS Registry Mumber 66608-11-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,6,6,0 and 8 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 66608-11:
(7*6)+(6*6)+(5*6)+(4*0)+(3*8)+(2*1)+(1*1)=135
135 % 10 = 5
So 66608-11-5 is a valid CAS Registry Number.
66608-11-5Relevant articles and documents
ARYL AND HETEROARYL-CARBOXAMIDE SUBSTITUTED HETEROARYL COMPOUNDS AS TYK2 INHIBITORS
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Page/Page column 57, (2021/10/15)
Novel carboxamide substituted compounds of Formula (I) are disclosed; as well as processes for their preparation, pharmaceutical compositions comprising them and their use in therapy as inhibitors of Tyrosine Kinase 2 (Tyk2).
