6661-54-7

Basic information

• Product Name: 2-butoxyethyl tosylate
• Synonyms: 2-butoxyethyl tosylate;NSC 312014;4-Methylbenzenesulfonic acid 2-butoxyethyl ester
• CAS NO: 6661-54-7
• Molecular Formula: C₁₃H₂₀O₄S
• Molecular Weight: 272.3605
• EINECS: 229-703-2
• Mol File: 6661-54-7.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 384.7°Cat760mmHg
• Flash Point: 186.4°C
• Appearance: /
• Density: 1.122g/cm³
• Vapor Pressure: 8.9E-06mmHg at 25°C
• Refractive Index: 1.5
• CAS DataBase Reference: 2-butoxyethyl tosylate(CAS DataBase Reference)
• NIST Chemistry Reference: 2-butoxyethyl tosylate(6661-54-7)
• EPA Substance Registry System: 2-butoxyethyl tosylate(6661-54-7)

Safety Data

• Hazardous Substances Data: 6661-54-7(Hazardous Substances Data)

Usage

Description

2-butoxyethyl tosylate is a chemical compound that serves as a reagent in organic synthesis, particularly as a tosylating agent. It is a clear, colorless liquid with a mild odor and is considered relatively safe to handle when used in a controlled manner.

Uses

Used in Organic Synthesis:
2-butoxyethyl tosylate is used as a tosylating agent for converting alcohols and phenols into their corresponding tosylates. This conversion is crucial in the synthesis of various organic compounds.
Used in Pharmaceutical Synthesis:
2-butoxyethyl tosylate is used as an intermediate in the synthesis of pharmaceuticals and other fine chemicals. Its ability to convert alcohols and phenols into tosylates makes it a valuable component in creating complex organic molecules for medicinal applications.
Used in Chemical Research:
In the field of chemical research, 2-butoxyethyl tosylate is used as a reagent to explore new reactions and mechanisms, contributing to the advancement of organic chemistry.
Proper handling and storage procedures should always be followed to ensure safety when using 2-butoxyethyl tosylate in any of these applications.

InChI:InChI=1/C13H20O4S/c1-3-4-9-16-10-11-17-18(14,15)13-7-5-12(2)6-8-13/h5-8H,3-4,9-11H2,1-2H3

Upstream product

• 111-76-2 2-Butoxyethanol 
• 98-59-9 p-toluenesulfonyl chloride 
• 133-59-5 Toluene-2-sulfonyl chloride 
• 824-79-3 sodium 4-methylbenzenesulfinate 

Downstream Products

• 54645-60-2 2-(2-Butoxy-ethoxy)-5-(2-dibenzylamino-acetyl)-benzamide 
• 4842-12-0 3-Jod-5-methoxycarbonyl-benzoesaeure-(2-butoxy-aethylester) 
• 4842-20-0 3-Jod-5-aethoxycarbonyl-benzoesaeure-(2-butoxy-aethylester) 
• 4862-99-1 3-Jod-5-propoxycarbonyl-benzoesaeure-(2-butoxy-aethylester) 
• 4863-06-3 3-Jod-5-butoxycarbonyl-benzoesaeure-(2-butoxy-aethylester) 
• 98654-34-3 (4-Acetamino-2-propionyl-phenyl)-(2-butyloxy-ethyl)-ether 
• 158937-13-4 1-carbomethoxy-4'-<<4-<<(n-butyloxy)ethyl>oxy>phenyl>ethynyl>biphenyl 
• 187748-44-3 2-n-butoxyethyl 2-benzyloxy-6-naphthoate 
• 63735-44-4 4-(2-butoxyethoxy)benzaldehyde 

Relevant articles and documents

MANUFACTURING METHOD OF 1,1-DISUBSTITUTED HYDRAZINE COMPOUND

PROBLEM TO BE SOLVED: To provide a manufacturing method of a 1,1-disubstituted hydrazine compound useful as a manufacturing intermediate. SOLUTION: There is provided a manufacturing method of a 1,1-disubstituted hydrazine compound represented by the formula (3) by reacting a hydrazino compound represented by the formula (1) with a compound represented by the formula (2): R-A in the presence of a correlation transfer catalyst, and a base such as alkali metal hydroxide, alkali earth metal hydroxide, and alkali metal alkoxide in a mixed solvent of water and a water insoluble organic solvent. In the formula, Q represents O, S or the like; R represents a C1 to 12 organic group which may have a substituent; A represents Cl, Br, a tosyl group or the like; Ra1 to Ra4 each independently represent H, a halogen atom, a C1 to 6 alkyl group, or the like. SELECTED DRAWING: None COPYRIGHT: (C)2020,JPOandINPIT

METHODS OF MAKING SUBSTITUTED PORPHYRIN PHARMACEUTICAL COMPOUNDS AND COMPOSITIONS

Described herein are methods and intermediates useful for making substituted porphyrins, including Mn(III) orthoN-butoxyethylpyridylporphyrin, and compositions comprising the same. In some embodiments, a method of the present invention provides a composition having a certain percentage or yield (e.g., at least 80%, 85%, 90%, or 95% by weight) of a compound of the present invention.

Synthesis and biological evaluation of novel 4-hydroxybenzaldehyde derivatives as tyrosinase inhibitors

A series of novel 4-hydroxybenzaldehyde derivatives were synthesized and their inhibitory effects on the diphenolase activity of mushroom tyrosinase were investigated. Most of target compounds had more potent inhibitory activities than the parent compound 4-hydroxybenzaldehyde (IC50 = 1.22 mM). Interestingly, compound 3c bearing a dimethoxyl phosphate was found to be the most potent inhibitor with IC50 value of 0.059 mM. The inhibition kinetics analyzed by Lineweaver-Burk plots revealed that compound 3c was a non-competitive inhibitor (KI = 0.0368 mM). In particular, compound 3c showed no side effects at dose of 1600 mg/kg in mice. These results suggested that such compounds might be served as lead compounds for further designing new potential tyrosinase inhibitors.