666236-04-0

Basic information

• Product Name: 5-(propane-2-sulfonyl)-1,3-dihydro-indol-2-one
• CAS NO: 666236-04-0
• Molecular Weight: 239.295
• Mol File: 666236-04-0.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 489.7±45.0 °C(Predicted)
• Density: 1.284±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 5-(propane-2-sulfonyl)-1,3-dihydro-indol-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(propane-2-sulfonyl)-1,3-dihydro-indol-2-one(666236-04-0)
• EPA Substance Registry System: 5-(propane-2-sulfonyl)-1,3-dihydro-indol-2-one(666236-04-0)

Safety Data

• Hazardous Substances Data: 666236-04-0(Hazardous Substances Data)

Upstream product

• 75-29-6 isopropyl chloride 
• 199328-31-9 2-oxo-2,3-dihydro-1H-indole-5-sulfonyl chloride 
• 59-48-3 2-oxoindole 

Relevant articles and documents

Design and synthesis of aminopropyl tetrahydroindole-based indolin-2-ones as selective and potent inhibitors of Src and Yes tyrosine kinase

A novel series of substituted 3-[3-(aminopropyl)-4,5,6,7-tetrahydro-1H- indol-2-ylmethylene]-1,3-dihydro-indole-2-ones was discovered as potent inhibitors of the non-receptor tyrosine kinase Src and Yes. A structure-activity relationship was developed in order to optimize their potency and selectivity. Syntheses of these compounds are also described herein.