666730-03-6

Basic information

• Product Name: Benzoic acid, 2-[(6,7-dimethoxy-4-quinolinyl)oxy]-5-methyl-, ethyl ester
• CAS NO: 666730-03-6
• Molecular Formula: C21H21NO5
• Molecular Weight: 367.401
• Mol File: 666730-03-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Benzoic acid, 2-[(6,7-dimethoxy-4-quinolinyl)oxy]-5-methyl-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 2-[(6,7-dimethoxy-4-quinolinyl)oxy]-5-methyl-, ethyl ester(666730-03-6)
• EPA Substance Registry System: Benzoic acid, 2-[(6,7-dimethoxy-4-quinolinyl)oxy]-5-methyl-, ethyl ester(666730-03-6)

Safety Data

• Hazardous Substances Data: 666730-03-6(Hazardous Substances Data)

Upstream product

• 35654-56-9 6,7-dimethoxy-4-chloroquinoline 
• 34265-58-2 ethyl 5-methylsalicylate 

Downstream Products

• 1032925-28-2 2-[(6,7-Dimethoxy-4-quinolyl)oxy]-5-methylbenzoic acid 

Relevant articles and documents

Synthesis and evaluation of [2-(4-quinolyloxy)phenyl]methanone derivatives: Novel selective inhibitors of transforming growth factor-β kinase

We synthesized and evaluated various [2-(4-quinolyloxy)phenyl]methanone derivatives. These compounds had novel chemical structures that were distinct from those of previously reported inhibitors. Biological data suggested that these compounds inhibited transforming growth factor-β signaling by interacting with the ATP-binding pocket of the transforming growth factor-β type I receptor kinase domain. Here, we report on the synthesis and structure-activity relationships of the compounds in this series.