66675-20-5Relevant articles and documents
Imidazole H-2 agonists. Synthesis and activity of 2-(2-amino-4-imidazolyl)ethylamine (2-aminohistamine) dihydrochloride
Vitali,Impicciatore,Plazzi,Bordi,Vitto
, p. 70 - 80 (2007/10/02)
The syntheses of 2-(2-amino-4-imidazolyl)ethylamine (2-aminohistamine) dihydrochloride and of the corresponding 5-methyl derivative are described. The histamine-like properties of the two salts are tested in vitro on isolated ileum and gastric fundus of guinea-pig. The results are discussed and compared with those of other H2-agonists.