666843-73-8

Basic information

• Product Name: Propanamide, 3-[[(2-nitrophenyl)sulfonyl]amino]-
• CAS NO: 666843-73-8
• Molecular Formula: C9H11N3O5S
• Molecular Weight: 273.269
• Mol File: 666843-73-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Propanamide, 3-[[(2-nitrophenyl)sulfonyl]amino]-(CAS DataBase Reference)
• NIST Chemistry Reference: Propanamide, 3-[[(2-nitrophenyl)sulfonyl]amino]-(666843-73-8)
• EPA Substance Registry System: Propanamide, 3-[[(2-nitrophenyl)sulfonyl]amino]-(666843-73-8)

Safety Data

• Hazardous Substances Data: 666843-73-8(Hazardous Substances Data)

Upstream product

• 64017-81-8 3-aminopropanamide hydrochloride 
• 1694-92-4 2-Nitrobenzenesulfonyl chloride 

Relevant articles and documents

PYRAZOLE DERIVATIVES, MEDICINAL COMPOSITION CONTAINING THE SAME, MEDICINAL USE THEREOF, AND INTERMEDIATE FOR PRODUCTION THEREOF

The present invention provides pyrazole derivatives represented by the general formula: wherein R1 represents H, an optionally substituted C1-6 alkyl group etc.; one of Q and T represents a group represented by the general formula: or a group represented by the general formula: while the other represents an optionally substituted C1-6 alkyl group etc.; R2 represents H, a halogen atom, OH, an optionally substituted C1-6 alkyl group etc.; X represents a single bond, O or S; Y represents an optionally substituted C1-6 alkylene group etc.; Z represents -RB, -CORC etc. in which RB represents an optionally substituted C1-6 alkyl group etc.; and RC represents an optionally substituted C1-6 alkyl group etc.,; R4 represents H, an optionally substituted C1-6 alkyl group etc.; and R3, R5 and R6 represent H, a halogen atom etc., pharmaceutically acceptable salts thereof or prodrugs thereof, which exhibit an excellent inhibitory activity in human SGLT1 and are useful as agents for the prevention or treatment of a disease associated with hyperglycemia such as diabetes, impaired glucose tolerance, impaired fasting glycemia, diabetic complications or obesity, and a disease associated with the increase of blood galactose level such as galactosemia, and pharmaceutical compositions comprising the same, pharmaceutical uses thereof, and intermediates for production thereof.