66713-28-8

Basic information

• Product Name: tert-Butyl 2,6-xylyl sulfoxide
• Synonyms: tert-Butyl 2,6-xylyl sulfoxide
• CAS NO: 66713-28-8
• Molecular Weight: 210.34
• Mol File: 66713-28-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: tert-Butyl 2,6-xylyl sulfoxide(CAS DataBase Reference)
• NIST Chemistry Reference: tert-Butyl 2,6-xylyl sulfoxide(66713-28-8)
• EPA Substance Registry System: tert-Butyl 2,6-xylyl sulfoxide(66713-28-8)

Safety Data

• Hazardous Substances Data: 66713-28-8(Hazardous Substances Data)

Upstream product

• 16463-11-9 2,6-dimethylphenyl 2-methyl-2-propyl sulfide 
• 2905-17-1 bis(2,6-dimethylphenyl)disulfide 
• 52805-90-0 2,2',6,6'-tetramethyldiphenyl sulfide 
• 594-19-4 tert.-butyl lithium 

Downstream Products

• 2905-17-1 bis(2,6-dimethylphenyl)disulfide 
• 66713-32-4 2,6-Xylyl 2,6-xylenethiosulfinate 
• 66713-33-5 2,6-Xylyl 2,5-xylenethiosulfonate 
• 66713-30-2 Methyl trans-<(2,6-xylyl)sulfinyl>acrylate 
• 66713-29-9 2-Hydroxysulfanyl-1,3-dimethyl-benzene 

Relevant articles and documents

Chemistry of Sulfenic Acids. 3. Studies of Sterically Hindered Sulfenic Acids Using Flash Vacuum Pyrolysis

Flash vacuum pyrolysis (FVP) of sulfoxides containing β-hydrogen atoms affords sulfenic acids (RSOH) in good concentration under conditions where they are stable.The application of this technique to the synthesis and study of sterically hindered sulfenic acids 12a-e is described.The principal or primary reaction of simple sulfenic acids prepared in this manner is dehydration to thiosulfinates 13 (eq 1).Steric inhibition to dehydration (eq 1) appears to only be of importance for 2-methyl-2-propanesulfenic acid (12a) which was trapped in good yield with methyl propiolate to afford 16a. 2,4,6-Tri-tert-butylbenzenesulfenic acid (12e) appears to be destabilized as a consequence of interaction between the SOH and adjacent tert-butyl groups.In the pyrolysis section of the apparatus, 12e decomposes to phenol 21 and aryl radical 22, which reacts further.Thermolysis of sulfoxides generates the sulfenic acids 12a-e in very low concentration at any one time.The products of sulfenic acids generated in this way result from secondary reactions of the corresponding thiosulfinates.