66820-51-7

Basic information

• Product Name: C₁₁H₁₂NO⁽¹⁺⁾*C₂H₆O₄P^(1-)
• Synonyms: C₁₁H₁₂NO⁽¹⁺⁾*C₂H₆O₄P^(1-)
• CAS NO: 66820-51-7
• Molecular Weight: 299.263
• Mol File: 66820-51-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₁H₁₂NO⁽¹⁺⁾*C₂H₆O₄P^(1-)(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₁H₁₂NO⁽¹⁺⁾*C₂H₆O₄P^(1-)(66820-51-7)
• EPA Substance Registry System: C₁₁H₁₂NO⁽¹⁺⁾*C₂H₆O₄P^(1-)(66820-51-7)

Safety Data

• Hazardous Substances Data: 66820-51-7(Hazardous Substances Data)

Upstream product

• 512-56-1 trimethyl phosphite 
• 529-37-3 4(1H)-quinolinone 
• 607-31-8 4-methoxyquinoline 
• 80-48-8 methyl p-toluene sulfonate 

Relevant articles and documents

Alkylation of Quinolines with Trialkyl Phosphates. Part 2. Mechanistic Studies

The mechanism of alkylation of 4-quinolone (3) by trialkyl phosphates has been studied by preparative, kinetic, and isotopic methods, as well as by u.v. spectrophotometry.In a kinetically controlled process the transient initial formation of 4-methoxyquinoline (4a) was established; this was subsequently transformed by trimethyl phosphate to a quaternary N-methyl-4-methoxyquinolinium salt (6a).The latter catalyses the transformation of (4a) by intermolecular ON methyl transfer to the more stable N-methyl-4-quinolone (5a).The end product is a mixture of (5a) and (6a).Their ratio is shifted at higher temperature in favour of (6a).This is due partly to differences in the temperature dependence of the individual reactions and partly to alkylation of (5a) by trimethyl phosphate at higher temperature.A mechanism for the alkylation reaction is proposed.