66875-54-5Relevant articles and documents
Acid-Mediated Three Component Assembly of 4-Fluoropyrazoles from α-Fluoronitroalkenes, Hydrazines, and Aldehydes
Ioffe, Sema L.,Motornov, Vladimir A.,Nelyubina, Yulia V.,Nenajdenko, Valentine G.,Tabolin, Andrey A.
, (2020/08/06)
A new approach for the synthesis of highly pharmaceutically relevant 4-fluoropyrazoles via oxidative annulation of α-fluoronitroalkenes with in situ prepared hydrazones was developed. The reaction is efficiently promoted by trifluoroacetic acid while atmo