669013-16-5Relevant articles and documents
A novel reagent for the chemical phosphorylation of oligonucleotides
Leuck, Michael,Vagle, Kurt E.,Roach, J. Shawn,Wolter, Andreas
, p. 321 - 324 (2007/10/03)
A novel phosphoramidite reagent was developed to convert terminal hydroxyl groups of oligonucleotides into phosphate monoesters. The reagent's appearance as a solid foam is advantageous for its manipulation and handling in solid phase synthesis and improves its thermal stability.