66936-19-4

Basic information

• Product Name: N₂-(6,7-dimethoxy-2-naphthalenesulfonyl)-L-arginyl-N-cyclohexylglycine tert-butyl ester
• CAS NO: 66936-19-4
• Molecular Weight: 619.783
• Mol File: 66936-19-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N₂-(6,7-dimethoxy-2-naphthalenesulfonyl)-L-arginyl-N-cyclohexylglycine tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: N₂-(6,7-dimethoxy-2-naphthalenesulfonyl)-L-arginyl-N-cyclohexylglycine tert-butyl ester(66936-19-4)
• EPA Substance Registry System: N₂-(6,7-dimethoxy-2-naphthalenesulfonyl)-L-arginyl-N-cyclohexylglycine tert-butyl ester(66936-19-4)

Safety Data

• Hazardous Substances Data: 66936-19-4(Hazardous Substances Data)

Upstream product

• 66937-55-1 N-cyclohexylglycine t-butyl ester 
• 63325-57-5 N₂-(6,7-dimethoxy-2-naphthalenesulfonyl)-L-arginyl chloride hydrochloride 
• 74-79-3 L-arginine 
• 63093-17-4 2-(6,7-Dimethoxynaphthalenyl)sulfonyl chloride 
• 63093-14-1 N₂-(6,7-dimethoxy-2-naphthalenesulfonyl)-L-arginine 

Downstream Products

• 66937-16-4 N₂-(6,7-dimethoxy-2-naphthalenesulfonyl)-L-arginyl-N-cyclohexylglycine 

Relevant articles and documents

Thrombin inhibitors. 3. Carboxyl-containing amide derivatives of N alpha-substituted L-arginine.

A series of N alpha-(arylsulfonyl)-L-arginine amide derivatives having carboxamide N-substituents with a carboxyl group was prepared and tested as inhibitors of the clotting activity of thrombin. The most inhibitory compounds were obtained when a carboxyl group was introduced into the carbon next to the amide nitrogen of N alpha-(arylsulfonyl)-L-arginine amide derivatives, e.g., N alpha-(arylsulfonyl)-L-arginyl-N-butyl-, N-(methoxyethyl)- or N-(tetrahydrofurfuryl)glycine and 4-alkyl-1-[N alpha-(arylsulfonyl)-L-arginyl]-2-piperidinecarboxylic acid, with an I50 of 1-3 X 10(-7) M.