66956-35-2

Basic information

• Product Name: 1-(3-chloro-4-methylphenyl)-1H-pyrazole
• Synonyms: 1-(3-chloro-4-methylphenyl)-1H-pyrazole
• CAS NO: 66956-35-2
• Molecular Weight: 192.648
• Mol File: 66956-35-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-(3-chloro-4-methylphenyl)-1H-pyrazole(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(3-chloro-4-methylphenyl)-1H-pyrazole(66956-35-2)
• EPA Substance Registry System: 1-(3-chloro-4-methylphenyl)-1H-pyrazole(66956-35-2)

Safety Data

• Hazardous Substances Data: 66956-35-2(Hazardous Substances Data)

Upstream product

• 288-13-1 NH-pyrazole 
• 95-49-8 2-methylchlorobenzene 
• 122-31-6 malondialdehyde bis(diethyl acetal) 
• 54812-56-5 1-(3-chloro-4-methylphenyl)hydrazine hydrochloride 

Relevant articles and documents

Teaching Old Compounds New Tricks: DDQ-Photocatalyzed C?H Amination of Arenes with Carbamates, Urea, and N-Heterocycles

The C?H amination of benzene derivatives was achieved using DDQ as photocatalyst and BocNH2 as the amine source under aerobic conditions and visible light irradiation. Electron-deficient and electron-rich benzenes react as substrates with moderate to good product yields. The amine scope of the reaction comprises Boc-amine, carbamates, pyrazoles, sulfonimides and urea. Preliminary mechanistic investigations indicate arene oxidation by the triplet of DDQ to radical cations with different electrophilicity and a charge transfer complex between the amine and DDQ as intermediate of the reaction.