66966-20-9

Basic information

• Product Name: (2S)-3-(O-ALLYLOXYPHENOXY)-1,2-EPOXYPROPANE
• Synonyms: (2S)-3-(O-ALLYLOXYPHENOXY)-1,2-EPOXYPROPANE
• CAS NO: 66966-20-9
• Molecular Formula: C₁₂H₁₄O₃
• Molecular Weight: 206.24
• Mol File: 66966-20-9.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (2S)-3-(O-ALLYLOXYPHENOXY)-1,2-EPOXYPROPANE(CAS DataBase Reference)
• NIST Chemistry Reference: (2S)-3-(O-ALLYLOXYPHENOXY)-1,2-EPOXYPROPANE(66966-20-9)
• EPA Substance Registry System: (2S)-3-(O-ALLYLOXYPHENOXY)-1,2-EPOXYPROPANE(66966-20-9)

Safety Data

• Hazardous Substances Data: 66966-20-9(Hazardous Substances Data)

Usage

Description

(2S)-3-(O-ALLYLOXYPHENOXY)-1,2-EPOXYPROPANE, also known as allyl glycidyl ether, is a colorless liquid chemical compound belonging to the class of epoxide compounds. It has a molecular formula of C12H14O3 and a molecular weight of 206.24 g/mol. This reactive compound is capable of undergoing various chemical reactions, such as ring-opening reactions, to form different derivatives and products.

Uses

Used in Polymer and Resin Production:
(2S)-3-(O-ALLYLOXYPHENOXY)-1,2-EPOXYPROPANE is used as a monomer in the production of polymers and resins. Its reactivity allows it to be incorporated into the polymerization process, contributing to the formation of various polymeric materials with specific properties for different applications.
Used in Chemical Synthesis:
Due to its ability to undergo ring-opening reactions and other chemical transformations, (2S)-3-(O-ALLYLOXYPHENOXY)-1,2-EPOXYPROPANE is used as an intermediate in the synthesis of various chemical compounds. This makes it a valuable building block in organic chemistry for creating a wide range of products.
It is important to handle (2S)-3-(O-ALLYLOXYPHENOXY)-1,2-EPOXYPROPANE with care due to its potential for skin and eye irritation, as well as its flammability. Proper safety measures should be taken during its use and storage to minimize risks.

Upstream product

• 141987-51-1 (R)-3-(2-allyloxy phenoxy)-1-chloro-2-propanol 
• 70987-78-9 (S)-Glycidyl tosylate 
• 1126-20-1 2-allyloxyphenol 
• 118712-60-0 S-oxiran-2-ylmethyl 4-nitrobenzenesulfonate 
• 115314-14-2 (2s)-(+)-glycidyl 3-nitrobenzenesulfonate 
• 6452-74-0 3-(o-Allyloxyphenoxy)-2-hydroxy-1-chlorpropan 
• 141987-34-0 Acetic acid 2-(2-allyloxy-phenoxy)-1-chloromethyl-ethyl ester 
• 51594-55-9 (R)-(-)-epichlorohydrin 

Downstream Products

• 6452-71-7 (-)-Oxprenolol 

Relevant articles and documents

PROCESS FOR PRODUCING GLYCIDYL ETHER

A process for producing a glycidyl ether and an optically active compound thereof with high yield and an optically high purity comprising reacting an alcohol with epihalohydrin in a base to thereby produce a glycidyl ether, the reaction performed in a two-layer system of a nonaqueous organic solvent and an aqueous solvent.

CsF in organic synthesis. Regioselective nucleophilic reactions of phenols with oxiranes leading to enantiopure β-blockers

The two modes of the paths in the reaction of oxiranes with phenols are completely controlled by CsF. Glycidyl nosylate undergoes exclusive substitution at the C1 position whereas the ring-opening (C-3 attack) occurs with epichlorohydrin, glycidol, and 1,2-epoxyalkanes. These reactions provide convenient access to enantiopure β-blockers.

Enzyme Assisted Preparation of Enantiomerically Pure β-Adrenergic Blockers III. Optically Active Chlorohydrin Derivatives and Their Conversion

Optical active chlorohydrin derivatives 2a-m and 3a-m of both enantiomeric series were prepared via both enzymatic hydrolyses and acyltransfer reactions catalysed by a highly selective lipase from Pseudomonas sp..The resulting building blocks were further transformed into the corresponding β-blockers of high enantiomeric purity.