6698-46-0

Basic information

• Product Name: 5-O-Benzoyl-1,2-O-isopropylidene-alpha-D-erythro-pent-3-ulofuranose
• Synonyms: 5-O-Benzoyl-1,2-O-isopropylidene-alpha-D-erythro-pent-3-ulofuranose;1,2-O-Isopropylidene-5-benzoate--alpha-D-erythro-Pentofuranos-3-ulose;5-O-Benzoyl-1,2-O-isopropylidene-3-keto-a-D-xylofuranoside;NSC 101766;1,2-O-(1-Methylethylidene)-alpha-D-erythro-pentofuranos-3-ulose benzoate;5-O-Benzoyl-1,2-di-O-isopropylidene-alpha-D-erythro-pent-3-ulofuranose
• CAS NO: 6698-46-0
• Molecular Formula: C₁₅H₁₆O₆
• Molecular Weight: 292.28394
• Mol File: 6698-46-0.mol
• Article Data: 31

Chemical Properties

• Melting Point: 93-94.5 °C
• Boiling Point: 411°C at 760 mmHg
• Flash Point: 182.4°C
• Appearance: /
• Density: 1.247g/cm³
• Vapor Pressure: 5.77E-07mmHg at 25°C
• Refractive Index: 1.521
• CAS DataBase Reference: 5-O-Benzoyl-1,2-O-isopropylidene-alpha-D-erythro-pent-3-ulofuranose(CAS DataBase Reference)
• NIST Chemistry Reference: 5-O-Benzoyl-1,2-O-isopropylidene-alpha-D-erythro-pent-3-ulofuranose(6698-46-0)
• EPA Substance Registry System: 5-O-Benzoyl-1,2-O-isopropylidene-alpha-D-erythro-pent-3-ulofuranose(6698-46-0)

Safety Data

• Hazardous Substances Data: 6698-46-0(Hazardous Substances Data)

Usage

Description

5-O-Benzoyl-1,2-O-isopropylidene-alpha-D-erythro-pent-3-ulofuranose is a chemical compound that serves as a key intermediate in the synthesis of various biologically active molecules. It is characterized by the presence of a benzoyl group at the 5-O position and an isopropylidene protecting group at the 1,2-O positions, with the alpha-D-erythro-pent-3-ulose core structure.

Uses

Used in Pharmaceutical Industry:
5-O-Benzoyl-1,2-O-isopropylidene-alpha-D-erythro-pent-3-ulofuranose is used as a key intermediate in the chemical synthesis of D-ribose, an essential component of nucleic acids and various other biological molecules. Its role in the synthesis process is crucial for the production of pharmaceuticals and other healthcare products.
Used in Biochemistry Research:
5-O-Benzoyl-1,2-O-isopropylidene-alpha-D-erythro-pent-3-ulofuranose is also utilized in the preparation of methylated nucleoside derivatives, which are important for studying the structure and function of nucleic acids and their interactions with proteins. The synthesis of these derivatives contributes to a better understanding of molecular biology and the development of new therapeutic agents.

InChI:InChI=1/C15H16O6/c1-15(2)20-12-11(16)10(19-14(12)21-15)8-18-13(17)9-6-4-3-5-7-9/h3-7,10,12,14H,8H2,1-2H3

Upstream product

• 6022-96-4 5-O-benzoyl-α-D-xylofuranose 
• 58-86-6 D-xylose 
• 98-88-4 benzoyl chloride 
• 20031-21-4 1,2-O-isopropylidene-α-D-xylose 
• 20881-04-3 1,2:3,5-di-O-isopropylidene-D-xylofuranose 
• 532-20-7 D-xylofuranose 
• 79-37-8 oxalyl dichloride 
• 16749-42-1 5,6-dideoxy-1,2-O-isopropylidene-α-D-xylo-hexofuranose 
• 67-64-1 acetone 

Downstream Products

• 28007-97-8 (6R)-5t-benzoyloxymethyl-2,2-dimethyl-(3at,6rN,6at)-dihydro-spiro[furo[2,3-d][1,3]dioxole-6,4'-imidazolidine]-2',5'-dione 
• 161821-79-0 1,2-isopropylidene-3-C-dimethylphosphono-5-O-benzoyl-α-D-ribofuranose 
• 250588-64-8 Benzoic acid (3aR,5R,6R,6aR)-6-cyano-6-hydroxy-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-ylmethyl ester 
• 130250-06-5 5-O-benzoyl-1,2-O-isopropylidene-3-C-<(benzyloxy)methylene>-α-D-ribofuranose 
• 144700-67-4 C₂₆H₂₅NO₇ 
• 37077-81-9 1,2-isopropylidene-α-D-ribofuranose 
• 29781-91-7 (E/Z)-5-O-Benzoyl-3-deoxy-3-hydroxyimino-1,2-O-isopropylidene-α-D-erythro-pentofuranose 
• 34304-33-1 5-O-benzoyl-1,2-O-isopropylidene-3-deoxy-3-nitro-D-ribofuranose 
• 34304-34-2 5-O-benzoyl-1,2-O-isopropylidene-3-deoxy-3-nitro-D-xylofuranose 
• 162894-32-8 ((3aR,5R,6R,6aR)-6-hydroxy-2,2-dimethyl-6-(trifluoromethyl)tetrahydrofuro[2,3-d][1,3]dioxol-5-yl)methyl benzoate 
• 59896-02-5 ((3aR,5S,6aR)-2,2-dimethyl-6-methylenetetrahydrofuro[2,3-d][1,3]dioxol-5-yl)methyl benzoate 
• 237070-16-5 1,2-O-isopropylidene-5-O-benzoyl-3-C-cyano-α-D-xylofuranose 
• 16831-81-5 ((3aR,5R,6R,6aR)-6-hydroxy-2,2,6-trimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)methyl benzoate 
• 64775-10-6 ((3aR,5S,6aR)-2,2-dimethyl-6-methylene-tetrahydrofuro[2,3-d][1,3]dioxol-5-yl)methanol 

Relevant articles and documents

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SYNTHESIS OF 1,2,5-TRI-0-BENZ0YL-3-DIBENZYLAMIN0-3-DE0XYRIB0SE AS INTERMEDIATE FOR PRODUCING 3'-AMINO-3'-DEOXYADENOSINE AND 3'-AMINO-3'-DEOXYGUANOSINE AND THE PROTECTED DERIVATIVES THEREOF

The invention generally relates to improved processes for the preparation of intermediates of a cyclic dinucleotide which is useful as a STING agonist.