670-74-6 Usage
General Description
2-[3-(trifluoromethyl)benzyl]benzonitrile is a chemical compound with the molecular formula C15H10F3N, consisting of a benzyl group attached to a benzene ring with a cyano group. It is also known as TFB, and is commonly used as a building block in the synthesis of pharmaceuticals and agrochemicals. TFB is a crystalline solid with a melting point of 62-65°C and a boiling point of 240-242°C. It is a highly reactive compound that is sensitive to air and moisture, and should be handled and stored with caution. Despite its potential hazards, TFB has a wide range of applications in the chemical industry due to its versatile reactivity and functional groups.
Check Digit Verification of cas no
The CAS Registry Mumber 670-74-6 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 6,7 and 0 respectively; the second part has 2 digits, 7 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 670-74:
(5*6)+(4*7)+(3*0)+(2*7)+(1*4)=76
76 % 10 = 6
So 670-74-6 is a valid CAS Registry Number.
670-74-6Relevant articles and documents
Transition-Metal-Free Cross-Coupling of Aryl and N-Heteroaryl Cyanides with Benzylic Zinc Reagents
Quinio, Pauline,Roman, Daniela Sustac,León, Thierry,William, Sharankini,Karaghiosoff, Konstantin,Knochel, Paul
supporting information, p. 4396 - 4399 (2015/09/15)
Functionalized 4-benzylated pyridines can be efficiently prepared by a transition-metal-free cross-coupling between various benzylic zinc chlorides and substituted 4-cyanopyridines in THF/DMPU under microwave irradiation (40 °C, 0.5-1.5 h). Selective benzylations on polycyano-aromatics have also been achieved under these mild conditions. We also report a novel oxidative nucleophilic substitution of a hydrogen on 1,3-dicyanobenzene using benzylic zinc reagents.
