67019-46-9

Basic information

• Product Name: 1,4-Dioxaspiro[4.5]dec-7-ene, 8-(4-methoxyphenyl)-
• CAS NO: 67019-46-9
• Molecular Formula: C15H18O3
• Molecular Weight: 246.306
• Mol File: 67019-46-9.mol
• Article Data: 15

Chemical Properties

• CAS DataBase Reference: 1,4-Dioxaspiro[4.5]dec-7-ene, 8-(4-methoxyphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,4-Dioxaspiro[4.5]dec-7-ene, 8-(4-methoxyphenyl)-(67019-46-9)
• EPA Substance Registry System: 1,4-Dioxaspiro[4.5]dec-7-ene, 8-(4-methoxyphenyl)-(67019-46-9)

Safety Data

• Hazardous Substances Data: 67019-46-9(Hazardous Substances Data)

Usage

Chemical structure

A complex structure consisting of a spiro ring and a methoxyphenyl group.

Molecular weight

246.30 g/mol

Functional groups

Contains a spiro ring, an oxygen atom, and a methoxy group.

Organic synthesis

Used in the preparation of various spirolactones.

Drug discovery and development

Potential applications in pharmaceutical research and development.

Material science

May have applications in material science.

Precursor

Can be used as a precursor for the synthesis of other complex organic compounds.

Biological activities

The unique structure makes it an interesting target for chemical research, and its potential biological activities make it an area of interest for pharmaceutical research and development.

Solubility

Information on solubility is not provided in the material, but it may be soluble in organic solvents like ethanol, methanol, or acetone.

Stability

Information on stability is not provided in the material, but it may be sensitive to heat, light, or moisture, which are common factors affecting the stability of organic compounds.

Reactivity

Information on reactivity is not provided in the material, but it may react with strong acids, strong bases, or oxidizing agents, which are common reactivity concerns for organic compounds.

Safety

Information on safety is not provided in the material, but it is essential to handle this compound with care, using appropriate safety measures such as gloves, eye protection, and a fume hood, as it may be toxic or harmful if inhaled, ingested, or absorbed through the skin.

Upstream product

• 680596-79-6 4,4,5,5-tetramethyl-2-(1,4-dioxaspiro[4.5]dec-7-en-8-yl)-1,3,2-dioxaborolane 
• 1580472-97-4 potassium (1,4-dioxaspiro[4.5]dec-7-en-8-yl)trifluoroborate 
• 4746-97-8 cyclohexanedione monoethylene ketal 
• 104-92-7 1-bromo-4-methoxy-benzene 
• 5720-07-0 4-methoxyphenylboronic acid 
• 170011-47-9 1,4-dioxaspiro[4.5]dec-7-en-8-yl trifluoromethanesulfonate 
• 91817-44-6 methyl 4-methoxy-1-(4-methoxyphenyl)-2-oxo-3-cyclohexenecarboxylate 
• 135530-16-4 Ethyl 8-(4-Methoxyphenyl)-1,4-dioxaspiro<4.5>dec-6-ene-8-carboxylate 
• 104331-21-7 Ethyl 1-(4-methoxyphenyl)-4-oxocyclohex-2-enecarboxylate 
• 83925-44-4 8-(methoxycarbonyl)-8-(4-methoxyphenyl)-1,4-dioxaspiro<4.5>dec-6-ene 
• 83925-40-0 4'-Methoxy-4-oxo-bicyclohexyl-2,2',4'-triene-1-carboxylic acid methyl ester 
• 83925-42-2 methyl 1-(4-methoxyphenyl)-4-oxo-2-cyclohexenecarboxylate 
• 67019-51-6 1-(4-methoxyphenyl)-1-hydroxycyclohexan-4-one ethylene ketal 
• 135530-20-0 8-Formyl-8-(4-methoxyphenyl)-1,4-dioxaspiro<4.5>dec-6-ene 

Downstream Products

• 5309-15-9 8-(4-methoxyphenyl)-1,4-dioxaspiro[4.5]decane 
• 1402080-48-1 5-(4-methoxyphenyl)oxepan-2-one 
• 1344674-28-7 (S)-9-(4-iodobenzyl)-3-(4-methoxyphenyl)-2,3,4,9-tetrahydro-1H-carbazole 
• 1344674-50-5 1-(4-iodobenzyl)-2-(4-(4-methoxyphenyl)cyclohexylidene)-1-phenylhydrazine 
• 5309-16-0 4-(4-methoxyphenyl)cyclohexanone 
• 868142-33-0 8-(4-methoxy-phenyl)-2,4-dioxo-1,3-diaza-spiro[4.5]decane-1,3-dicarboxylic acid di-tert-butyl ester 
• 868142-07-8 8-(4-methoxy-phenyl)-1,3-diaza-spiro[4.5]decane-2,4-dione 

Relevant articles and documents

Photocatalyzed Transition-Metal-Free Oxidative Cross-Coupling Reactions of Tetraorganoborates**

Readily accessible tetraorganoborate salts undergo selective coupling reactions under blue light irradiation in the presence of catalytic amounts of transition-metal-free acridinium photocatalysts to furnish unsymmetrical biaryls, heterobiaryls and arylated olefins. This represents an interesting conceptual approach to forge C?C bonds between aryl, heteroaryl and alkenyl groups under smooth photochemical conditions. Computational studies were conducted to investigate the mechanism of the transformation.

Enantioselective Synthesis of Chiral Oxime Ethers: Desymmetrization and Dynamic Kinetic Resolution of Substituted Cyclohexanones

Axially chiral cyclohexylidene oxime ethers exhibit unique chirality because of the restricted rotation of C=N. The first catalytic enantioselective synthesis of novel axially chiral cyclohexylidene oximes has been developed by catalytic desymmetrization of 4-substituted cyclohexanones with O-arylhydroxylamines and is catalyzed by a chiral BINOL-derived strontium phosphate with excellent yields and good enantioselectivities. In addition, chiral BINOL-derived phosphoric acid catalyzed dynamic kinetic resolution of α-substituted cyclohexanones has been performed and yields versatile intermediates in high yields and enantioselectivities.

Catalytic asymmetric hydrogenation of α-arylcyclohexanones and total synthesis of (-)-α-lycorane

An efficient catalytic asymmetric hydrogenation of racemic α-arylcyclohexanones with an ethylene ketal group at the 5-position of the cyclohexane ring via dynamic kinetic resolution has been developed, giving chiral α-arylcyclohexanols with two contiguous