6703-30-6 Usage
Description
(1R,2R,4R)-1,7,7-trimethylbicyclo[2.2.1]heptane-2-carboxylic acid, also known as bornane carboxylic acid, is a bicyclic organic compound characterized by a carboxylic acid group attached to a bicyclo[2.2.1]heptane ring system. This colorless, solid compound with a strong odor is recognized for its rigid and chiral structure, which makes it a versatile and valuable compound in the pharmaceutical industry and organic chemistry research.
Uses
Used in Pharmaceutical Industry:
(1R,2R,4R)-1,7,7-trimethylbicyclo[2.2.1]heptane-2-carboxylic acid serves as a chiral building block for the synthesis of various drugs and biologically active compounds. Its unique stereochemistry is crucial for the development of enantiomerically pure pharmaceuticals, ensuring the desired therapeutic effects and minimizing potential side effects.
Used as a Starting Material in Asymmetric Synthesis:
Due to its rigid and chiral structure, (1R,2R,4R)-1,7,7-trimethylbicyclo[2.2.1]heptane-2-carboxylic acid is often used as a starting material for the preparation of chiral catalysts and ligands. These catalysts and ligands are essential in asymmetric synthesis, a technique that allows for the selective formation of one enantiomer of a chiral compound over another, which is particularly important in the production of pharmaceuticals and agrochemicals.
Used in Organic Chemistry Research and Development:
The unique structure and properties of (1R,2R,4R)-1,7,7-trimethylbicyclo[2.2.1]heptane-2-carboxylic acid make it a valuable compound for research and development in the field of organic chemistry. It can be utilized to explore new reaction pathways, develop innovative synthetic methods, and create novel compounds with potential applications in various industries.
Check Digit Verification of cas no
The CAS Registry Mumber 6703-30-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,7,0 and 3 respectively; the second part has 2 digits, 3 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 6703-30:
(6*6)+(5*7)+(4*0)+(3*3)+(2*3)+(1*0)=86
86 % 10 = 6
So 6703-30-6 is a valid CAS Registry Number.
6703-30-6Relevant articles and documents
Rearrangement approaches to cyclic skeletons. IX. Stereoselective total synthesis of (±)-camphorenone based on a ring-contraction of bicyclo[3.2.1]oct-6-en-2-one. Reliable one-step diazo transfer followed by a Wolff rearrangement
Uyehara,Takehara,Ueno,Sato
, p. 2687 - 2694 (2007/10/03)
A direct diazo transfer reaction to bicyclo[3.2.1]oct-6-en-2-ones and related compounds was accomplished by treatments with 2,4,6-triisopropylbenzenesulfonyl azide and potassium t-butoxide at -78°C in THF. A Wolff rearrangement of the resulting α-diazoketones in the presence of water gave ring-contraction products, bicyclo[2.2.1]heptenecarboxylic acids. Using these two transformations the total synthesis of (±)-camphorenone was achieved stereoselectively, starting from 1-methoxybicyclo[2.2.2]oct-5-en-2-one.