67077-40-1Relevant articles and documents
Palladium-Catalyzed Enantioselective Redox-Relay Heck Alkynylation of Alkenols To Access Propargylic Stereocenters
Chen, Zhi-Min,Nervig, Christine S.,DeLuca, Ryan J.,Sigman, Matthew S.
supporting information, p. 6651 - 6654 (2017/05/29)
An enantioselective redox-relay Heck alkynylation of di- and trisubstituted alkenols to construct propargylic stereocenters is disclosed using a new pyridine oxazoline ligand. This strategy allows direct access to chiral β-alkynyl carbonyl compounds employing allylic alcohol substrates in contrast to more traditional conjugate addition methods.
