67157-60-2

Basic information

• Product Name: Benzoic acid, 2-methyl-, phenylmethyl ester
• CAS NO: 67157-60-2
• Molecular Formula: C15H14O2
• Molecular Weight: 226.275
• Mol File: 67157-60-2.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: Benzoic acid, 2-methyl-, phenylmethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 2-methyl-, phenylmethyl ester(67157-60-2)
• EPA Substance Registry System: Benzoic acid, 2-methyl-, phenylmethyl ester(67157-60-2)

Safety Data

• Hazardous Substances Data: 67157-60-2(Hazardous Substances Data)

Upstream product

• 118-90-1 ortho-methylbenzoic acid 
• 100-51-6 benzyl alcohol 
• 70063-30-8 o-Carboxyphenylperessigsaeure-tert.-butylester 
• 529-20-4 2-methylphenyl aldehyde 
• 89-95-2 2-methyl-benzyl alcohol 
• 108-88-3 toluene 
• 95-46-5 2-methylphenyl bromide 
• 104-57-4 benzyl formate 
• 39627-62-8 1-(o-tolyl)-2-propen-1-ol 
• 89-71-4 2-Methyl-benzoic acid methyl ester 
• 703-59-3 homophthalic anhydride 
• 908094-04-2 phenyldiazomethane 
• 100-44-7 benzyl chloride 
• 3469-06-5 benzocyclobutenone 

Downstream Products

• 108-88-3 toluene 
• 100-51-6 benzyl alcohol 
• 118-90-1 ortho-methylbenzoic acid 
• 620-83-7 1-methyl-4-(phenylmethyl)benzene 
• 713-36-0 2-benzyltoluene 

Relevant articles and documents

Bu 4 NI-Catalyzed C-C Bond Cleavage and Oxidative Esteri??cation of Allyl Alcohols with Toluene Derivatives

A novel oxidative esterification of 1-arylprop-2-en-1-ols with toluene derivatives catalyzed by tetrabutylammonium iodide (TBAI) is reported. The optimization of the reaction conditions illustrates that each of experiment parameters including the catalyst, solvent, and oxidant is significant for present oxidative functionalization. This metal-free protocol has a broad substrate scope including the halogen groups for further functionalization and enriches the reactivity profile of allyl alcohol and toluene derivatives. In addition, this protocol represents a new transformation of allyl alcohol involving C-C bond cleavage and C-O bond forming.

METHOD OF CONVERTING ALCOHOL TO HALIDE

The present invention relates to a method of converting an alcohol into a corresponding halide. This method comprises reacting the alcohol with an optionally substituted aromatic carboxylic acid halide in presence of an N-substituted formamide to replace a hydroxyl group of the alcohol by a halogen atom. The present invention also relates to a method of converting an alcohol into a corresponding substitution product. The second method comprises: (a) performing the method of the invention of converting an alcohol into the corresponding halide; and (b) reacting the corresponding halide with a nucleophile to convert the halide into the nucleophilic substitution product.

Cooperative N-Heterocyclic Carbene (NHC) and Ruthenium Redox Catalysis: Oxidative Esterification of Aldehydes with Air as the Terminal Oxidant

The paper describes a cooperative NHC (N-heterocyclic carbene) and ruthenium-based redox catalysis for the mild aerobic oxidative esterification of various aromatic and heteroaromatic aldehydes. The ruthenium(II) complex Ru(bpz)3(PF6)2 (bpz=2,2′-bipyrazine) as catalyst is shown to be compatible with free NHCs. The NHC is used in these cascade reactions for the umpolung of the aldehyde to form the corresponding Breslow intermediate which in turn gets oxidized to an acylazolium ion by the ruthenium redox catalyst. Air is used as a terminal oxidant for oxidation (regeneration) of the ruthenium catalyst. In addition, we will show that in the absence of the ruthenium redox catalyst and alcohol, NHC-catalyzed aerobic oxidation of aldehydes delivers the corresponding acids in good to excellent yields. Mechanistic studies and DFT calculations supporting our suggested mechanisms are provided. Copyright