672263-60-4

Basic information

• Product Name: Benzene, 1-chloro-4-(1-pentynyl)-
• CAS NO: 672263-60-4
• Molecular Formula: C11H11Cl
• Molecular Weight: 178.661
• Mol File: 672263-60-4.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Benzene, 1-chloro-4-(1-pentynyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1-chloro-4-(1-pentynyl)-(672263-60-4)
• EPA Substance Registry System: Benzene, 1-chloro-4-(1-pentynyl)-(672263-60-4)

Safety Data

• Hazardous Substances Data: 672263-60-4(Hazardous Substances Data)

Upstream product

• 637-87-6 1-Chloro-4-iodobenzene 
• 627-19-0 1-Pentyne 
• 106-39-8 bromochlorobenzene 
• 18270-17-2 1-trimethylsilyl-1-pentyne 

Downstream Products

• 1402355-11-6 (E)-1-(1-bromo-2-(1-phenylethyl)pent-1-enyl)-4-chlorobenzene 
• 1402355-12-7 (Z)-1-(1-bromo-2-(1-phenylethyl)pent-1-enyl)-4-chlorobenzene 
• 1346260-59-0 1-(4-chlorophenyl)pentane-1,2-dione 
• 14670-41-8 (Z)-1-chloro-4-(pent-1-en-1-yl)benzene 
• 92328-81-9 (+/-)-1--1-propylamino-pentan 

Relevant articles and documents

Regio- and Stereoselective Cyanotriflation of Alkynes Using Aryl(cyano)iodonium Triflates

A novel, mild, and versatile approach for regioselective syn-addition of both the CN and OTf groups of aryl(cyano)iodonium triflates to alkynes is described. The reaction uses Fe-catalysis and can be conducted in gram scale. Products of the vicinal cyanotriflation can be stereospecifically readily further functionalized, rendering the method highly valuable.

Stereodivergent zinc-mediated three-component synthesis of tri- and tetrasubstituted alkenes

Zinc simple: The loading-dependent zinc-mediated addition of benzyl bromides to alkynes is the key step for the formation of vinyl bromides. In combination with a palladium-catalyzed Suzuki cross-coupling reaction with boronic acids, tri- and tetrasubstit

C(sp2)-C(sp) and C(sp)-C(sp) Coupling Reactions Catalyzed by Oxime-Derived Palladacycles

Oxime-derived chloro-bridged palladacycle 8a, derived from 4,4′-dichlorobenzophenone, is an efficient pre-catalyst for the copper- and amine-free Sonogashira coupling between terminal acetylenes and aryl iodides and aryl and vinyl bromides achieving turnover numbers (TON) of up to 72000. Catalyst 8a has also been shown as a effective promoter for the sila-Sonogashira coupling between 1-(trimethylsilyl)alkynes and aryl iodides and bromides in the presence of CuI or Bu4NBr as co-catalysts. This complex also catalyzes efficiently the homocoupling reaction (Glaser-type coupling) between 1-alkynes in NMP at room temperature with TONs of up to 1000. All the reactions can be performed under air and employing reagent-grade chemicals under very low loading conditions, which demonstrates the versatility and high activity of oxime-derived palladacycles.