67227-57-0 Usage
Description
8-Chloro-2-(4-hydroxyphenyl)-4-azabicyclo[5.4.0]undeca-7,9,11-triene-9,10-diol methanesulphonate is a complex organic compound with a unique chemical structure. It is characterized by its bicyclic ring system, which includes a chlorine atom and a hydroxyphenyl group. 8-Chloro-2-(4-hydroxyphenyl)-4-azabicyclo[5.4.0]undeca-7,9,11-triene-9,10-diol methanesulphonate has a molecular formula of C16H16ClNO4S and a molecular weight of approximately 363.83 g/mol. Its chemical properties and potential applications make it a compound of interest in various fields.
Uses
Used in Pharmaceutical Industry:
8-Chloro-2-(4-hydroxyphenyl)-4-azabicyclo[5.4.0]undeca-7,9,11-triene-9,10-diol methanesulphonate is used as an active pharmaceutical ingredient (API) for the development of antihypertensive and dopamine agonist drugs. Its unique chemical structure allows it to interact with specific receptors in the body, providing therapeutic benefits for patients suffering from hypertension and related conditions.
Used in Research and Development:
8-Chloro-2-(4-hydroxyphenyl)-4-azabicyclo[5.4.0]undeca-7,9,11-triene-9,10-diol methanesulphonate is used as a research compound to study dopamine D1-mediated cell signaling. Its agonistic properties towards dopamine D1A (D1R) and D1B (D5R) receptors make it a valuable tool for understanding the roles of these receptors in cellular processes and their potential as targets for therapeutic intervention.
Used in Drug Delivery Systems:
In the field of drug delivery, 8-Chloro-2-(4-hydroxyphenyl)-4-azabicyclo[5.4.0]undeca-7,9,11-triene-9,10-diol methanesulphonate can be employed as a component in the development of novel drug delivery systems. Its chemical properties may allow for the creation of carriers or vehicles for the compound, improving its delivery, bioavailability, and therapeutic outcomes in various applications.
Used in Chemical Synthesis:
8-Chloro-2-(4-hydroxyphenyl)-4-azabicyclo[5.4.0]undeca-7,9,11-triene-9,10-diol methanesulphonate can also be used as a starting material or intermediate in the synthesis of other complex organic compounds. Its unique structure and functional groups make it a potentially useful building block for the development of new pharmaceuticals, agrochemicals, or other specialty chemicals.
Therapeutic Function
Antihypertensive
Biochem/physiol Actions
Fenoldopam mesylate (FM) is considered as an effective therapeutic agent to prevent the onset of postoperative AKI (PO-AKI). In healthy cats, FM can stimulate diuresis and be well-tolerated. This benzazepine-derivative is regional specific and does not cause cerebral vasodilation.
Check Digit Verification of cas no
The CAS Registry Mumber 67227-57-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,7,2,2 and 7 respectively; the second part has 2 digits, 5 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 67227-57:
(7*6)+(6*7)+(5*2)+(4*2)+(3*7)+(2*5)+(1*7)=140
140 % 10 = 0
So 67227-57-0 is a valid CAS Registry Number.
InChI:InChI=1/C16H16ClNO3.CH4O3S/c17-15-11-5-6-18-8-13(9-1-3-10(19)4-2-9)12(11)7-14(20)16(15)21;1-5(2,3)4/h1-4,7,13,18-21H,5-6,8H2;1H3,(H,2,3,4)
67227-57-0Relevant articles and documents
CRYSTALLINE FORMS FENOLDOPAM MESYLATE
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Page/Page column 18-19, (2010/11/26)
The invention provides new crystalline forms of fenoldopam mesylate, i.e. fenoldopam mesylate Type I, fenoldopam mesylate Type III, fenoldopam mesylate Type V, and fenoldopam mesylate Type VI, methods of preparing the crystalline forms, and pharmaceutical compositions comprising the fenoldopam mesylate crystalline forms of the invention.
Solid oral preparation containing a pyrrolidine derivative with a catechol group
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, (2008/06/13)
An oral solid preparation comprising an organic acid or its salt and a catechol compound. The catechol compound is, for example, a pyrrolidine derivative having a catechol group of the following general formula (I). It exhibits an improved absorbability in vivo. STR1
