672325-36-9 Usage
General Description
(3R)-1-(2-Aminoethyl)-3-pyrrolidinol, also known as (R)-(-)-1-(2-Aminoethyl)pyrrolidin-3-ol or (R)-3-Aminomethyl-3-methyl-1-pyrrolidinol, is a chemical compound with the molecular formula C7H15NO and a molecular weight of 129.20 g/mol. It is an amino alcohol that is commonly used as a chiral building block in the synthesis of pharmaceuticals, agrochemicals, and other fine chemicals. It is also used as a chiral resolving agent and a ligand in asymmetric catalysis. (3R)-1-(2-Aminoethyl)-3-pyrrolidinol is a colorless to pale yellow liquid at room temperature and is soluble in water and ethanol. It is important in organic synthesis due to its ability to form stable complexes with metal ions, making it useful in various catalytic reactions.
Check Digit Verification of cas no
The CAS Registry Mumber 672325-36-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,7,2,3,2 and 5 respectively; the second part has 2 digits, 3 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 672325-36:
(8*6)+(7*7)+(6*2)+(5*3)+(4*2)+(3*5)+(2*3)+(1*6)=159
159 % 10 = 9
So 672325-36-9 is a valid CAS Registry Number.
InChI:InChI=1/C6H14N2O/c7-2-4-8-3-1-6(9)5-8/h6,9H,1-5,7H2/t6-/m1/s1
672325-36-9Relevant articles and documents
SAR study of bicyclo[4.1.0]heptanes as melanin-concentrating hormone receptor R1 antagonists: Taming hERG
Su, Jing,McKittrick, Brian A.,Tang, Haiqun,Burnett, Duane A.,Clader, John W.,Greenlee, William J.,Hawes, Brian E.,O'Neill, Kim,Spar, Brian,Weig, Blair,Kowalski, Timothy,Sorota, Steve,Li, Cheng,Liu, Tongtong
, p. 5369 - 5385 (2008/03/14)
To improve the ex vivo potency of MCH inhibitor 1a and to address its hERG liability, a structure-activity study was carried out, focusing on three regions of the lead structure. Introduction of new side chains with basic nitrogen improved in vitro and ex