67279-23-6

Basic information

• Product Name: 2,3,5,6,7,8-Hexahydrophthalazine-1,4-dione
• Synonyms: 2,3,5,6,7,8-Hexahydrophthalazine-1,4-dione
• CAS NO: 67279-23-6
• Molecular Formula: C8H10N2O2
• Molecular Weight: 166.1772
• Mol File: 67279-23-6.mol
• Article Data: 11

Chemical Properties

• Melting Point: 295-298 °C
• Boiling Point: 462.6°Cat760mmHg
• Flash Point: 233.6°C
• Appearance: /
• Density: 1.31g/cm³
• Vapor Pressure: 3.53E-09mmHg at 25°C
• Refractive Index: 1.578
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 10.00±0.20(Predicted)
• CAS DataBase Reference: 2,3,5,6,7,8-Hexahydrophthalazine-1,4-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3,5,6,7,8-Hexahydrophthalazine-1,4-dione(67279-23-6)
• EPA Substance Registry System: 2,3,5,6,7,8-Hexahydrophthalazine-1,4-dione(67279-23-6)

Safety Data

• Hazardous Substances Data: 67279-23-6(Hazardous Substances Data)

Usage

General Description

2,3,5,6,7,8-Hexahydrophthalazine-1,4-dione is a chemical compound with the molecular formula C8H8O2N2. It is a cyclic compound that contains a six-membered ring with two nitrogen atoms and two carbonyl groups. 2,3,5,6,7,8-Hexahydrophthalazine-1,4-dione has been studied for its potential therapeutic applications, including its role as a central nervous system depressant and antihypertensive agent. It is also used in the synthesis of other organic compounds and pharmaceuticals. Additionally, 2,3,5,6,7,8-Hexahydrophthalazine-1,4-dione is known for its ability to form stable complexes with metal ions, making it of interest in coordination chemistry and metal ion sensing applications. Overall, this compound has diverse potential uses and applications in various fields of chemistry and pharmacology.

InChI:InChI=1/C8H10N2O2/c11-7-5-3-1-2-4-6(5)8(12)10-9-7/h1-4H2,(H,9,11)(H,10,12)

Upstream product

• 2426-02-0 3,4,5,6-Tetrahydrophthalic anhydride 

Downstream Products

• 67279-24-7 1,4-dichloro-5,6,7,8-tetrahydrophthalazine 
• 1057682-44-6 1-chloro-4-(4-fluoro-benzyl)-5,6,7,8-tetrahydro-phthalazine 
• 1057681-34-1 4-{4-[4-(4-fluoro-benzyl)-5,6 7,8-tetrahydro-phthalzin-1-yl]-piperazin-1-yl}-nicotinonitrile 

Relevant articles and documents

THRB RECEPTOR AGONIST COMPOUND AND PREPARATION METHOD AND USE THEREOF

The present invention discloses a compound represented by the following Formula (I) and a pharmaceutically acceptable salt thereof. The compound improves the THRα selectivity while maintaining good THRβ agonistic activity, thereby improving properties of

TRIAZOLOPYRIDAZINES AS PAR1 INHIBITORS, PRODUCTION THEREOF, AND USE AS MEDICAMENTS

The invention relates to novel compounds of formula I where R1, R2, R3, R4, R5, R6, R7, R8, Q1, Q2 and Q3 are each as defined below. The compounds of formula I have antithrombotic activity and inhibit especially protease-activated receptor 1 (PAR1). The i

Organic Compounds as Smo Inhibitors

The present invention relates generally to novel compounds relating to the diagnosis and treatment of pathologies relating to the Hedgehog pathway, including but not limited to tumor formation, cancer, neoplasia, and non-malignant hyperproliferative disorders. The present invention includes novel compounds, novel compositions, methods of their use and methods of their manufacture, where such compounds are generally pharmacologically useful as agents in therapies whose mechanism of action involve methods of inhibiting tumorigenesis, tumor growth and tumor survival using agents that inhibit the Hedgehog and Smo signaling pathway.