672906-71-7 Usage
General Description
(S)-N-Methyl-1-[4-(trifluoromethyl)phenyl]ethylamine is a chemical compound that belongs to the class of aromatic amines. It is a chiral compound, meaning it has a non-superimposable mirror image, and the (S)-enantiomer refers to the left-handed version of the molecule. (S)-N-METHYL-1-[4-(TRIFLUOROMETHYL)PHENYL]ETHYLAMINE is often used as a building block in organic synthesis, particularly in the pharmaceutical and agrochemical industries. Its trifluoromethyl group makes it a valuable molecule for drug design and development, as this functional group can influence the bioavailability, pharmacokinetics, and biological activity of the resulting compounds. Additionally, the phenyl group in its structure gives it a certain level of aromaticity, which can also be important for its chemical reactivity and biological activity.
Check Digit Verification of cas no
The CAS Registry Mumber 672906-71-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,7,2,9,0 and 6 respectively; the second part has 2 digits, 7 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 672906-71:
(8*6)+(7*7)+(6*2)+(5*9)+(4*0)+(3*6)+(2*7)+(1*1)=187
187 % 10 = 7
So 672906-71-7 is a valid CAS Registry Number.
InChI:InChI=1/C10H12F3N/c1-7(14-2)8-3-5-9(6-4-8)10(11,12)13/h3-7,14H,1-2H3/t7-/m0/s1
672906-71-7Relevant articles and documents
Direct Asymmetric Hydrogenation of N-Methyl and N-Alkyl Imines with an Ir(III)H Catalyst
Salomó, Ernest,Gallen, Albert,Sciortino, Giuseppe,Ujaque, Gregori,Grabulosa, Arnald,Lledós, Agustí,Riera, Antoni,Verdaguer, Xavier
supporting information, p. 16967 - 16970 (2018/12/14)
A novel cationic [IrH(THF)(P,N)(imine)] [BArF] catalyst containing a P-stereogenic MaxPHOX ligand is described for the direct asymmetric hydrogenation of N-methyl and N-alkyl imines. This is the first catalytic system to attain high enantioselectivity (up to 94% ee) in this type of transformation. The labile tetrahydrofuran ligand allows for effective activation and reactivity, even at low temperatures. Density functional theory calculations allowed the rationalization of the stereochemical course of the reaction.
