67320-92-7

Basic information

• Product Name: LEU-PRO TRIFLUOROACETATE SALT
• Synonyms: H-LEU-PRO-OH TFA;LEU-PRO TRIFLUOROACETATE SALT;L-LEUCYL-L-PROLINE TRIFLUOROACETATE SALT;leu-pro trifluoroacetate;1-L-Leucyl-L-proline mono(trifluoroacetate);(S)-1-((S)-2-Amino-4-methylpentanoyl)pyrrolidine-2-carboxylic acid compound with 2,2,2-trifluoroacetic acid (1:1)
• CAS NO: 67320-92-7
• Molecular Formula: C₂HF₃O₂*C₁₁H₂₀N₂O₃
• Molecular Weight: 342.31
• Product Categories: Dipeptides;Dipeptides and Tripeptides;Peptides
• Mol File: 67320-92-7.mol
• Article Data: 2

Chemical Properties

• Appearance: white/powder
• Storage Temp.: −20°C
• CAS DataBase Reference: LEU-PRO TRIFLUOROACETATE SALT(CAS DataBase Reference)
• NIST Chemistry Reference: LEU-PRO TRIFLUOROACETATE SALT(67320-92-7)
• EPA Substance Registry System: LEU-PRO TRIFLUOROACETATE SALT(67320-92-7)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 67320-92-7(Hazardous Substances Data)

Upstream product

• 76-05-1 trifluoroacetic acid 
• 64205-66-9 (tert-butoxycarbonyl)-L-leucyl-L-proline 
• 13139-15-6 N-tert-butoxycarbonyl-L-leucine 
• 83610-44-0 benzyl (2S)-1-[(2S)-2-{[(tert-butoxy)carbonyl]amino}-4-methylpentanoyl]pyrrolidine-2-carboxylate 
• 41324-66-7 H-Pro-OBzl 
• 68624-06-6 (S)-methyl 1-((S)-2-(tert-butoxycarbonylamino)-4-methylpentanoyl)pyrrolidine-2-carboxylate 

Downstream Products

• 79113-01-2 Boc-Asp(OBzl)-Leu-Pro-OH 
• 123-72-8 butyraldehyde 
• 590-86-3 isovaleraldehyde 

Relevant articles and documents

Synthesis and kinetics of oxidation of some dipeptides with anodically generated manganese(III) sulphate: Mechanistic study

Dipeptides (DP) namely phenylalanyl-proline (Phe-Pro), isoleucyl-proline (Ile-Pro), and leucyl-proline (Leu-Pro) were synthesized by classical solution method and characterized. The kinetics of oxidation of these DP by Mn(III) have been studied in the presence of sulphate ions in acidic medium at 26°C. The reaction was followed spectrophotometrically at λmax = 500 nm. A first-order dependence of rate on both [Mn(III)]0 and [DP]0 was observed. The rate is independent of the concentration of reduction product, Mn(II), and hydrogen ions. The effects of varying dielectric constant of the medium and addition of anions such as sulphate, chloride, and perchlorate were studied. The activation parameters have been evaluated using Arrhenius and Eyring plots. The oxidation products were isolated and characterized. A mechanism involving the reaction of DP with Mn(III) in the rate-limiting step is suggested.