67398-48-5

Basic information

• Product Name: Cyclopentanecarboxamide, N-(4-bromophenyl)-4,4-dimethyl-2-oxo-
• CAS NO: 67398-48-5
• Molecular Formula: C14H16BrNO2
• Molecular Weight: 310.191
• Mol File: 67398-48-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Cyclopentanecarboxamide, N-(4-bromophenyl)-4,4-dimethyl-2-oxo-(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclopentanecarboxamide, N-(4-bromophenyl)-4,4-dimethyl-2-oxo-(67398-48-5)
• EPA Substance Registry System: Cyclopentanecarboxamide, N-(4-bromophenyl)-4,4-dimethyl-2-oxo-(67398-48-5)

Safety Data

• Hazardous Substances Data: 67398-48-5(Hazardous Substances Data)

Upstream product

• 1807-68-7 diazodimedone 
• 106-40-1 4-bromo-aniline 

Downstream Products

• 1395329-06-2 C₂₀H₂₀BrNO₂ 
• 1395329-51-7 C₂₄H₂₂BrNO₂ 
• 1395330-11-6 C₂₄H₂₂BrNO₂ 

Relevant articles and documents

PPh3-Catalyzed [3 + 2] Spiroannulation of 1C,3N-Bisnucleophiles Derived from Secondary β-Ketoamides with δ-Acetoxy Allenoate: A Route to Functionalized Spiro N-Heterocyclic Derivatives

A [3 + 2] annulation of α-substituted secondary β-ketoamides with δ-acetoxy-modified allenoate has been developed in the presence of phosphine catalyst. In this spiroannulation reaction, β-ketoamides were used as the bis-nucleophilic partner while the γ,δ-carbon of 5-acetoxypenta-2,3-dienoate participated as a C2 synthon, affording the desired functionalized five-membered N-heterocyclic derivatives in moderate to excellent yields and diastereoselectivities under mild conditions. Preliminary attempts on the asymmetric variant of this reaction have been also examined, giving the corresponding products with moderate ee values.