67452-85-1 Usage
Description
1-Benzoyl-3-piperidinone is a chemical compound synthesized from 3-Hydroxypiperidine, which is a metabolite of Piperidine, an organic heterocyclic amine. Piperidine is widely used as a building block and reagent in the synthesis of various organic compounds, including pharmaceuticals.
Uses
Used in Pharmaceutical Industry:
1-Benzoyl-3-piperidinone is used as a reagent for the synthesis of trisubstituted ureas, which act as thrombin receptor (PAR-1) antagonists. These antagonists have potential applications in the development of medications for the treatment of various medical conditions, such as cardiovascular diseases and coagulation disorders.
Additionally, 1-Benzoyl-3-piperidinone is used as a building block in the synthesis of other organic compounds and pharmaceuticals, contributing to the development of new drugs and therapeutic agents.
Check Digit Verification of cas no
The CAS Registry Mumber 67452-85-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,7,4,5 and 2 respectively; the second part has 2 digits, 8 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 67452-85:
(7*6)+(6*7)+(5*4)+(4*5)+(3*2)+(2*8)+(1*5)=151
151 % 10 = 1
So 67452-85-1 is a valid CAS Registry Number.
67452-85-1Relevant articles and documents
Preparation method N-substituted piperidine -3- ketone (by machine translation)
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Paragraph 0094-0097, (2020/03/25)
The invention provides N -substituted piperi- 3 3-ketone preparation method, which uses acrylonitrile (II) and nitromethane as raw materials to obtain 4 -substituted-N-alkoxycarbonylmethyl- 4 4-aminobutyronitrile (III), to obtain 4 - substituent - N N-alkoxycarbonylmethyl( (IV),substituted-piperi- 3 3-one N - by addition reaction and decarboxylation to yield (V),substituted-piperidin-3-one according. to the present invention by two-time substituent reaction, reaction, and decarboxylation to obtain, a compound obtained from, N -substituted-piperidin-3-one of, the invention. (I). The method is simple, process and, times of reaction and decarboxylation. (by machine translation)