6749-54-8

Basic information

• Product Name: 1-phenylethyl p-toluenesulfonate
• Synonyms: 1-phenylethyl p-toluenesulfonate
• CAS NO: 6749-54-8
• Molecular Weight: 276.356
• Mol File: 6749-54-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1-phenylethyl p-toluenesulfonate(CAS DataBase Reference)
• NIST Chemistry Reference: 1-phenylethyl p-toluenesulfonate(6749-54-8)
• EPA Substance Registry System: 1-phenylethyl p-toluenesulfonate(6749-54-8)

Safety Data

• Hazardous Substances Data: 6749-54-8(Hazardous Substances Data)

Upstream product

• 13466-30-3 1-(2-methylphenyl)hydrazonoethane 
• 75067-08-2 benzene 
• 98-85-1 1-Phenylethanol 

Downstream Products

• 4013-34-7 3-phenyl-2-oxabutane 
• 33863-82-0 4-methyl-N-(1-phenylethyl)aniline 
• 881846-79-3 4-chloro-N-(1-phenylethyl)benzenamine 
• 779-54-4 phenyl(1-phenylethyl)amine 
• 5350-86-7 anti-2,3-Diphenylbutanoic acid 
• 5350-86-7 syn-2,3-Diphenylbutanoic acid 
• 1092840-22-6 N'-phenylhydrazine carboxylic acid 1-phenylethyl ester 
• 259195-14-7 trithiocarbonic acid bis(1-phenylethyl) ester 
• 2040-37-1 benzyl 1-phenylethyl ether 
• 126522-56-3 4-methoxy-N-(1-phenylethyl)aniline 

Relevant articles and documents

Reaction of Hydrazones with Methoxy(tosyloxy)iodobenzene (MTIB): Tosylate Formation under Oxidative Conditions

Treatment of aromatic hydrazones 1 containing electron-withdrawing, reduction sensitive substituents with MTIB gives the corresponding tosylates 2 in high yield. When the tosylate is particularly reactive the thermodynamically more stable methyl ether 3 is isolated. Analogous reactions with DAIB give acetates 4 in high yield. Dialkyl hydrazones give olefinic products (e.g. 7 and 8). (+)-Camphor hydrazone 1k with either MTIB or DAIB gives both camphene 12 (major product) and tricyclene 11 (minor product) suggesting that a carbene pathway accounts for some of the material formed in these oxidations.

Arylalkyl amines useful for lowering intraocular pressure

Intraocular hypertensive diseases such as glaucoma are treated with compounds represented by formula I STR1 or a pharmaceutically acceptable acid addition salt thereof, wherein R1 is alkyl of two to four carbon atoms; R2 is --(CH2)n --C6 H4 --R5 ; where n is an integer from 1 to 4; and R5 is --H, --OH, halo, lower alkyl, lower alkoxy, ureido, lower alkyl-ureido, lower alkyl-amido, or formamido; R3 is hydro or hydroxy; and R4 is hydro, lower alkyl, amino, or lower alkylamino.