675148-96-6Relevant articles and documents
PHENYL mTORC INHIBITORS AND USES THEREOF
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Paragraph 00316, (2018/05/27)
The present invention provides compounds, compositions thereof, and methods of using the same.
SPIRO-SUBSTITUTED OXINDOLE DERIVATIVES HAVING AMPK ACTIVITY
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Page/Page column 78; 79, (2015/01/07)
The present invention relates to compounds of formula (I), which have valuable pharmacological properties, in particular are activators of AMPK and which are therefore useful in the treatment of certain disorders that can be prevented or treated by activation of this receptor. The compounds are suitable for treatment and prevention of diseases which can be influenced by this receptor, such as metabolic diseases, in particular diabetes type 2.
NOVEL INDOLE DERIVATIVES USEFUL AS ANTI-DIABETIC AGENTS
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Page/Page column 122; 124, (2014/09/29)
Novel compounds of the structural formula (I) are activators of AMP-protein kinase and may be useful in the treatment, prevention and suppression of diseases mediated by the AMPK-activated protein kinase. The compounds of the present invention may be useful in the treatment of Type 2 diabetes, hyperglycemia, metabolic syndrome, obesity, hypercholesterolemia, and hypertension.