67521-01-1 Usage
Chemical compound
2H-Benzimidazol-2-one,5-acetyl-1,3-dihydro-6-methyl-(9CI)
Type
Heterocyclic compound
Structure
Benzimidazole core structure
Use
Building block for synthesis of pharmaceuticals and agrochemicals
Applications
Development of drugs for cancer, infectious diseases, and CNS disorders
Versatility
Useful in medicinal chemistry research and drug development
Synthetic versatility
Important target for further studies in organic and medicinal chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 67521-01-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,7,5,2 and 1 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 67521-01:
(7*6)+(6*7)+(5*5)+(4*2)+(3*1)+(2*0)+(1*1)=121
121 % 10 = 1
So 67521-01-1 is a valid CAS Registry Number.
67521-01-1Relevant articles and documents
FRIDEL-CRAFTS ACYLATION OF BENZIMIDAZOLIN-2-ONES WITH ALIPHATIC ACID CHLORIDES
Kadyrov, Ch. Sh.,Khalikov, S. S.
, p. 658 - 661 (2007/10/02)
The acylation of benzimidazolin-2-one and its 5,6-disubstituted derivatives with aliphatic acid chlorides in the presence of anhydrous aluminium chloride was studied.The corresponding 5(6)-acyl-, 5-R-6-acyl, and 5,6-dimethyl-4-acylbenzimidazolin-2-ones, the structures of which were confirmed by the results of elementary analysis and IR, PMR, and mass spectroscopy, were obtained.The yields of the acylation products depend on the electronic effects of the substituents in the benzene ring of the benzimidazolin-2-one on steric factors.
