67567-19-5

Basic information

• Product Name: 7-(2,2,6-trimethylcyclohexen-1-yl)-5-methyl-2,4,6-heptatrienal
• Synonyms: 7-(2,2,6-trimethylcyclohexen-1-yl)-5-methyl-2,4,6-heptatrienal
• CAS NO: 67567-19-5
• Molecular Formula: C₁₇H₂₄O
• Molecular Weight: 244.37
• Mol File: 67567-19-5.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 7-(2,2,6-trimethylcyclohexen-1-yl)-5-methyl-2,4,6-heptatrienal(CAS DataBase Reference)
• NIST Chemistry Reference: 7-(2,2,6-trimethylcyclohexen-1-yl)-5-methyl-2,4,6-heptatrienal(67567-19-5)
• EPA Substance Registry System: 7-(2,2,6-trimethylcyclohexen-1-yl)-5-methyl-2,4,6-heptatrienal(67567-19-5)

Safety Data

• Hazardous Substances Data: 67567-19-5(Hazardous Substances Data)

Upstream product

• 5560-99-6 (2X,4E)-3-methyl-5-(2,6,6-trimethyl-cyclohex-1-enyl)-penta-2,4-dienal 
• 73198-78-4 α-(Trimethylsilyl)-tert-butylacetaldimine 
• 6980-79-6 (2E,4E,6E)-5-methyl-7-(2’,6’,6’-trimethylcyclohex-1’-en-1’-yl)-hepta-2,4,6-trienenal 
• 107508-18-9 7-cis-β-ionylidenecrotonaldehyde 
• 14398-58-4 (2E,4Z,6E)-5-Methyl-7-(2,6,6-trimethyl-cyclohex-1-enyl)-hepta-2,4,6-trien-1-ol 
• 6153-05-5 (Z)-3-methylpent-2-en-4-ynol 
• 2408-37-9 2,2,6-trimethylcyclohexan-1-one 
• 187339-51-1 (2Z,4E)-3-methyl-5-(1-hydroxy-2,2,6-trimethylcyclohexyl)-pent-2,4-dien-1-ol 
• 187409-93-4 1-(5-hydroxy-3-methyl-pent-3-en-1-ynyl)-2,2,6-trimethyl-cyclohexanol 
• 187339-52-2 (2Z,4E)-3-methyl-5-(1-hydroxy-2,2,6-trimethylcyclohexyl)-pent-2,4-dien-1-al 
• 187339-53-3 (2E,4Z,6E)-7-(1-Hydroxy-2,2,6-trimethyl-cyclohexyl)-5-methyl-hepta-2,4,6-trienoic acid methyl ester 
• 58526-71-9 (2E,4E,6E)-5-methyl-7-(2’,6’,6’-trimethylcyclohex-1’-en-1’-yl)-hepta-2,4,6-trienenal 
• 79-77-6 4-(2,6,6-trimethyl-1-cyclohexen-1-yl)-3-buten-2-one 
• 3917-41-7 (2E,4E)-3-methyl-5-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4-pentadienal 

Downstream Products

• 1220-77-5 6-methyl-8-(2,6,6-trimethyl-1-cyclohexenyl)-3,5,7-octatriene-2-one 
• 6980-79-6 (2E,4E,6E)-5-methyl-7-(2’,6’,6’-trimethylcyclohex-1’-en-1’-yl)-hepta-2,4,6-trienenal 
• 107508-18-9 7-cis-β-ionylidenecrotonaldehyde 
• 78769-76-3 (3E,5Z,7E)-6-Methyl-8-(2,6,6-trimethyl-cyclohex-1-enyl)-octa-3,5,7-trien-2-ol 
• 187339-54-4 C₁₈H₂₅⁽²⁾H₃O 
• 187339-55-5 (2E,4Z,6E)-1-³H₃C,5-methyl-7-(2,2,6-trimethylcyclohex-1-enyl)-hepta-2,4,6-triene-1-ol 
• 302-79-4 9-cis-retinoic acid 
• 58526-50-4 [7t,9c,11t,13t]retinoic acid methyl ester 
• 187339-56-6 C₁₈H₂₃⁽²⁾H₃O 
• 187339-57-7 (2E,4Z,6E)-1-³H₃C,5-methyl-7-(2,2,6-trimethylcyclohex-1-enyl)-hepta-2,4,6-triene-1-one 
• 187339-58-8 C₂₁H₂₇⁽²⁾H₃O₂ 
• 187339-59-9 methyl-(2E,4E,6Z,8E)-3-³H₃C,7-methyl-9-(2,2,6-trimethylcyclohex-1-enyl)-nona-2,4,6,8-tetraenoate 
• 116-31-4 all-trans-Retinal 
• 99302-30-4 retinal 

Relevant articles and documents

A synthesis method of 9-cis Beta-carotene

The present invention relates to a method for synthesizing 9 - cis Beta-carotene (9 - cis beta-carotene) compounds having high purity and easy mass production through a chemical reaction, and a reaction for substituting 9 - cis Retinol groups of Alcohol with 9 - cis Phosphonium salt. The reaction of β - (3 - Methyl-2-butenal to Knoevenagel condensation) to synthesize All-trans Aldehyde. In step 9 - cis Retinoic Phosphonium salt) and in step), the completed All-trans Aldehyde is subjected to Wittig Olefination reaction with carbon double bonds, and 9. cis Beta-carotene obtained by the reaction of carbon double bonds.

Synthesis of 9-cis-retinoic acid and C-20-[3H3C]-9-cis-retinoic acid with high specific activity

The synthesis of 9-cis-retinoic acid starting from 2,2,6-trimethylcyclohexanone is described. The same methodology was extended for the synthesis of deuterium and tritium labeled 9-cis-retinoic acid with high specific activity (73 Ci/mmol). In this methodology, a Grignard reaction was utilized for introducing three tritium atoms simultaneously in the final synthetic steps.

Synthesis of 8-, 9-, 12-, and 13-mono-13C-retinal

The 8-, 9-, 12-, and 13-mono-13C-retinals were synthesized with >98percent chemical purity and 93percent 13C incorporation from 13C-labelled acetonitrile.Their 13C-13C and 13C-1H nmr coupling constants were determined.