67587-20-6Relevant articles and documents
Total synthesis and configurational validation of (+)-violapyrone C
Lee, Jong Seok,Shin, Junho,Shin, Hee Jae,Lee, Hwa-Sun,Lee, Yeon-Ju,Lee, Hyi-Seung,Won, Hoshik
supporting information, p. 4472 - 4476 (2014/08/05)
Gold(I)-catalyzed intramolecular 6-endo-dig cyclization of tert-butyl ynoates afforded α-pyrone cores of violapyrones. Moreover, this reaction was successfully applied to the stereospecific syntheses of (+)- and (-)-violapyrone C, which allowed the absolute configuration of natural (+)-violapyrone C to be assigned by comparison of the optical rotations. This first total synthesis, which proceeded in 22% yield over 10 steps from (S)-(-)-2-methylbutanol, features silver(I) oxide promoted monobenzylation of 1,4-butanediol, Wittig olefination, Claisen condensation, Corey-Fuchs reaction, and gold(I)-catalyzed α-pyrone synthesis. Copyright
Electrochemical selective incorporation of CO2 into terminal alkynes and diynes
Ko?ster, Frank,Dinjus, Erkhardt,Din?ach, Elisabet
, p. 2507 - 2511 (2007/10/03)
Electrochemical incorporation of CO2 into terminal alkynes and diynes on silver cathodes occurred selectively, to afford monocarboxylic acid derivatives in good yields. The electrolyses were carried out in one-compartment cells fitted with magnesium anodes, under mild conditions.