67596-84-3 Usage
Description
(R)-1,2,3,4,5,6,7,8-octahydro-1-[(4-methoxyphenyl)methyl]-2-methylisoquinoline, commonly known as (R)-meptazinol, is a synthetic compound with a unique structure that closely resembles the opioid agonist morphine. It functions as a mixed agonist-antagonist at opioid receptors, offering pain relief with a reduced risk of addiction and respiratory depression compared to traditional opioids. This characteristic makes (R)-meptazinol a valuable asset in the field of pain management.
Uses
Used in Pharmaceutical Industry:
(R)-meptazinol is used as an opioid analgesic for the treatment of moderate to severe pain. Its mixed agonist-antagonist activity at opioid receptors allows it to provide effective pain relief while minimizing the potential for addiction and respiratory depression, making it a safer alternative to conventional opioids.
Used in Pain Management:
(R)-meptazinol is used as a pain management agent due to its ability to activate kappa opioid receptors, which may contribute to its analgesic effects. Its lower potential for abuse and dependence compared to other opioids makes it a preferred choice for certain patient populations, particularly those with a history of substance abuse or those who require long-term pain management.
Used in Research and Development:
(R)-meptazinol's unique mechanism of action and structural similarities to morphine make it an important compound for research and development in the field of pharmacology. It can be used to study the effects of opioid agonist-antagonists on pain relief and addiction, potentially leading to the development of new, safer, and more effective pain management therapies.
Check Digit Verification of cas no
The CAS Registry Mumber 67596-84-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,7,5,9 and 6 respectively; the second part has 2 digits, 8 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 67596-84:
(7*6)+(6*7)+(5*5)+(4*9)+(3*6)+(2*8)+(1*4)=183
183 % 10 = 3
So 67596-84-3 is a valid CAS Registry Number.
InChI:InChI=1/C18H25NO/c1-19-12-11-15-5-3-4-6-17(15)18(19)13-14-7-9-16(20-2)10-8-14/h7-10,18H,3-6,11-13H2,1-2H3/t18-/m1/s1
67596-84-3Relevant articles and documents
A process for preparing dextromethorphan method
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, (2018/02/04)
The invention relates to a novel method for preparing dextromethorphan. When the method is used for preparing an intermediate (+)-1-(4-methoxy) benzyl-1,2,3,4,5,6,7,8-hexahydroisoquinoline (VI), a catalytic reducing method is adopted to carry out chiral reduction on 1-(4-methoxy) benzyl-3,4,5,6,7,8-hexahydroisoquinoline (VI), so that the intermediate is prepared with high selectivity. The novel method disclosed by the invention can cancel complex operations such as chiral resolution, is simple to operate, gentle in reaction condition, short in total time, wide in material source, and very suitable for industrially producing dextromethorphan.
