67600-79-7

Basic information

• Product Name: 1-Pyrazolidinecarboxylic acid, phenylMethyl ester
• Synonyms: 1-Pyrazolidinecarboxylic acid, phenylMethyl ester;Benzyl pyrazolidine-1-carboxylate;Benzyl Pyrazolidine-1-Carboxylate(WX604642)
• CAS NO: 67600-79-7
• Molecular Formula: C₁₁H₁₄N₂O₂
• Molecular Weight: 206.24106
• Mol File: 67600-79-7.mol
• Article Data: 10

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C(protect from light)
• CAS DataBase Reference: 1-Pyrazolidinecarboxylic acid, phenylMethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Pyrazolidinecarboxylic acid, phenylMethyl ester(67600-79-7)
• EPA Substance Registry System: 1-Pyrazolidinecarboxylic acid, phenylMethyl ester(67600-79-7)

Safety Data

• Hazardous Substances Data: 67600-79-7(Hazardous Substances Data)

Usage

General Description

1-Pyrazolidinecarboxylic acid, phenylmethyl ester is a chemical compound with the molecular formula C11H13N3O2. It is an ester derivative of pyrazolidinecarboxylic acid, a compound commonly used in the synthesis of pharmaceuticals, agrochemicals, and veterinary products. The phenylmethyl ester of 1-Pyrazolidinecarboxylic acid is often used as an intermediate or building block in organic synthesis. It may also have potential applications in the development of new drugs or as a reagent in chemical research. However, caution should be exercised when handling this compound, as it may have hazardous properties and should be used in accordance with proper safety protocols and regulations.

Upstream product

• 57699-89-5 pyrazolidine-1,2-dicarboxylic acid 1-benzyl ester 2-tert-butyl ester 
• 501-53-1 benzyl chloroformate 
• 89990-54-5 pyrazolidine dihydrogen chloride 
• 802982-86-1 4,5-dihydropyrazole-1-carboxylic acid benzyl ester 
• 57699-88-4 1-tert-butoxycarbonyl-2-carbobenzyloxyhydrazine 
• 5331-43-1 N-benzyloxycarbonyl-hydrazine 

Downstream Products

• 648958-43-4 2-methoxyoxalyl-pyrazolidine-1-carboxylic acid benzyl ester 
• 802982-86-1 4,5-dihydropyrazole-1-carboxylic acid benzyl ester 
• 745018-19-3 2-[2-(4-fluorophenyl)acetyl]pyrazolidine-1-carboxylic acid benzyl ester 
• 648958-45-6 2-(3,3-dimethyl-2-oxo-pentanoyl)-pyrazolidine-1-carboxylic acid benzyl ester 
• 852164-75-1 2-(2-ethoxycarbonyl-acetyl)-pyrazolidine-1-carboxylic acid benzyl ester 

Relevant articles and documents

Histamine H3 Inverse Agonists and Antagonists and Methods of Use Thereof

Provided herein are fused imidazolyl compounds, methods of synthesis, and methods of use thereof. The compounds provided herein are useful for the treatment, prevention, and/or management of various disorders, including, e.g., neurological disorders and metabolic disorders. Compounds provided herein inhibit the activity of histamine H3 receptors and modulate the release of various neurotransmitters, such as, e.g., histamine, acetylcholine, norepinephrine, and dopamine (e.g. at the synapse). Pharmaceutical compositions containing the compounds and their methods of use are also provided herein.

Preparation of new monomers aza-β3-aminoacids for solid-phase syntheses of aza-β3-peptides

The preparation of new Nβ-Fmoc-protected aza-β3-amino acids (aza-β3-aa) with proteinogenic side chains as well as their Nβ-Fmoc, Nβ-Cbz or Nβ-Boc aza-β3-amino esters (from Pro, Asn, Asp, Glu, Gln) by successive nucleophilic substitutions will be described.

Facile scalable reduction of N-acylated dihydropyrazoles

The reduction of a variety of highly functionalized N-acylated dihydropyrazoles (1) with BH3-pyridine is described. The process through which this unexpectedly difficult reduction was discovered and developed is reported. A facile atom-efficien