6761-17-7

Basic information

• Product Name: Benzamide, N-(4-oxo-2-phenyl-3(4H)-quinazolinyl)-
• CAS NO: 6761-17-7
• Molecular Formula: C21H15N3O2
• Molecular Weight: 341.369
• Mol File: 6761-17-7.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Benzamide, N-(4-oxo-2-phenyl-3(4H)-quinazolinyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzamide, N-(4-oxo-2-phenyl-3(4H)-quinazolinyl)-(6761-17-7)
• EPA Substance Registry System: Benzamide, N-(4-oxo-2-phenyl-3(4H)-quinazolinyl)-(6761-17-7)

Safety Data

• Hazardous Substances Data: 6761-17-7(Hazardous Substances Data)

Upstream product

• 1022-46-4 2-phenyl-4H-3,1-benzoxazin-4-one 
• 1904-60-5 3-amino-2-phenylquinazolin-4(3H)-one 
• 98-88-4 benzoyl chloride 
• 118-92-3 anthranilic acid 
• 7510-49-8 methyl 2-(benzamido)benzoate 
• 134-20-3 2-carbomethoxyaniline 
• 1904-58-1 anthranilic acid hydrazide 
• 613-94-5 benzoic acid hydrazide 
• 43100-29-4 N-benzoyl-N'-(N-benzoyl-anthraniloyl)-hydrazine 

Relevant articles and documents

Asymmetric Synthesis of N-N Axially Chiral Compounds by Phase-Transfer-Catalyzed Alkylations

N-N axially chiral skeletons are significant structural motifs in natural products, pharmaceuticals, and functional materials. Herein we disclose a method for the asymmetric synthesis of N-N axially chiral compounds by phase-transfer catalysis. A wide range of N-N axially chiral quinazolinone derivatives were prepared in high yields with excellent stereoselectivities. Furthermore, the synthetic utility of the protocol was proved by large-scale reaction and transformation of the product. Density functional theory calculations provide insight into the mechanism.

Pd-catalyzed intramolecular aerobic oxidative C-H amination of 2-aryl-3-(arylamino)quinazolinones: Synthesis of fluorescent indazolo[3,2-b]quinazolinones

A palladium-catalyzed intramolecular aerobic oxidative C-H amination of 2-aryl-3-(arylamino)quinazolinones has been developed, providing a variety of substituted indazolo[3,2-b]quinazolinone derivatives in moderate to excellent yields. Preliminary mechani

Quinazolinones with amide linkage: Synthesis and antimicrobial activity

Treatment of anthranilic acid in pyridine with benzoyl chloride gives 2-phenyl-3,1-benzoxazine-4-one (I). 3-Amino-2-phenylquinazol-4-one (II) was synthesized by reaction of 2-phenyl-3,1-benzoxazine-4-one I with hydrazine hydrate (80%) in ethanol. Aseries of amides were synthesized by treatment of various substituted acid chlorides with 3amino-2-phenylquinazol-4-one using pyridine as solvent. All the synthesized compounds were characterized by elemental analysis and spectral data. They were screened for antibacterial activity against E. coli and S. aureus and for antifungal activity against A. niger by cup plate method at 1 μg/ml cone in DMF. All the synthesized compounds showed good to moderate antimicrobial activity.