676457-76-4Relevant articles and documents
N-bromosuccinimide promoted synthesis of β-amino bromides under Appel reaction condition
Chinthaginjala, Srinivasulu,Alavandimat, Nanda H.,Umesha, Vathsala,Sureshbabu, Vommina V.
supporting information, p. 2975 - 2983 (2021/08/27)
An efficient and facile method has been developed for the synthesis of chiral β-amino bromides from their corresponding alcohols under Appel reaction conditions. This approach allows for the deoxybromination of a variety of β-amino alcohols in excellent y
Diastereoselective control of intramolecular aza-Michael reactions using achiral catalysts
Zhong, Cheng,Wang, Yikai,Hung, Alvin W.,Schreiber, Stuart L.,Young, Damian W.
supporting information; experimental part, p. 5556 - 5559 (2011/12/05)
An intramolecular aza-Michael reaction with a Cbz carbamate and an enone is reported to result in 3,5-disubstituted nitrogen-containing heterocycles. Either cis or trans isomers were obtained selectively using chiral substrates and an achiral Pd (II) comp
Synthesis of 2,6-disubstituted piperazines by a diastereoselective palladium-catalyzed hydroamination reaction
Cochran, Brian M.,Michael, Forrest E.
, p. 329 - 332 (2008/09/19)
(Chemical Equation Presented) A highly diastereoselective intramolecular hydroamination is the key step in a modular synthesis of 2,6-disubstituted piperazines. The requisite hydroamination substrates were prepared in excellent yields by nucleophilic disp