67650-38-8

Basic information

• Product Name: 1-epi-sisomicin
• Synonyms: 1-epi-sisomicin
• CAS NO: 67650-38-8
• Molecular Weight: 447.532
• Mol File: 67650-38-8.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 1-epi-sisomicin(CAS DataBase Reference)
• NIST Chemistry Reference: 1-epi-sisomicin(67650-38-8)
• EPA Substance Registry System: 1-epi-sisomicin(67650-38-8)

Safety Data

• Hazardous Substances Data: 67650-38-8(Hazardous Substances Data)

Upstream product

• 66065-86-9 3,2',6'-tri-N-acetylsisomicin 
• 66065-91-6 3,2',6'-tri-N-acetyl-1-deamino-1-oxosisomicin 
• 66065-86-9 N-[(1S,2R,3R,4S)-2-[(2S,3R)-3-Acetylamino-6-(acetylamino-methyl)-3,4-dihydro-2H-pyran-2-yloxy]-5-amino-4-((2R,3R,4R,5R)-3,5-dihydroxy-5-methyl-4-methylamino-tetrahydro-pyran-2-yloxy)-3-hydroxy-cyclohexyl]-acetamide 

Downstream Products

• 2037-48-1 2-deoxystreptamine 
• 2037-48-1 1-epi-2-deoxystreptamine 

Relevant articles and documents

Process for the preparation of purified aminoglycoside antibiotics

The invention relates to an improved process for the isolation and purification of aminoglycoside antibiotics of Formula (I) as defined herein combining selective lipophilization of the compound of Formula (I) in the crude product obtained by fermentation with controlled liquid/liquid extraction.

Aminoglycoside 66-40C, method for its manufacture, method for its use as an intermediate in the preparation of known antibiotics and novel antibacterials

Aminoglycoside 66-40C, a minor product produced by the fermentation of Micromonospora inyoensis, is separated from said fermentation mixture, and is used as an intermediate in preparing the known antibiotic, sisomicin, as well as 6' -N-alkylsisomicins having antibacterial activity. Claimed are Aminoglycoside 66-40C as well as 6' -N-t-alkylsisomicins having a tertiary carbon bonded to the 6' -nitrogen.