676560-15-9Relevant articles and documents
Unsymmetrical α,ω-end-functionalized oligo(cyclohexylidenes): efficient synthesis and conformational analysis
Zeinyeh, Wa?l,Radix, Sylvie,Terreux, Rapha?l,Chemelle, Julie-Anne,Walchshofer, Nadia
, p. 4032 - 4038 (2016)
The title compounds were efficiently synthesized by decarboxylative dehydration of β-hydroxy acids. This iterative process allowed to obtain bis- and ter-cyclohexylidenes with good yield. The conformations of trans and cis isomers of an unsymmetrical α,ω-
TRICYCLIC COMPOUND SERVING AS IMMUNOMODULATOR
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Paragraph 0809-0810, (2019/01/04)
Provided are compounds of formula I and formula II or pharmaceutically acceptable salts of the compounds and pharmaceutical compositions thereof. The compounds of formula I and formula II or the pharmaceutically acceptable salts of the compounds provide indole 2,3-dioxygenase (IDO) inhibitory activity and are capable of treating IDO-mediated immunosuppressive diseases, such as infectious diseases or cancer.
AMIDO-SUBSTITUTED CYCLOHEXANE DERIVATIVES
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Page/Page column 118; 119, (2018/05/24)
The present invention relates to amido-substituted cyclohexane compounds of general formula (I) : in which m, A, R4, R6, R7, R8, R9, R10 and R11 are as defined herein, to methods of preparing said compounds, to intermediate compounds useful for preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, in particular of neoplasms, as a sole agent or in combination with other active ingredients.
