676626-91-8

Basic information

• Product Name: 5(4H)-Oxazolone, 4-[(3,4-dimethylphenyl)methylene]-2-methyl-, (4Z)-
• CAS NO: 676626-91-8
• Molecular Formula: C13H13NO2
• Molecular Weight: 215.252
• Mol File: 676626-91-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 5(4H)-Oxazolone, 4-[(3,4-dimethylphenyl)methylene]-2-methyl-, (4Z)-(CAS DataBase Reference)
• NIST Chemistry Reference: 5(4H)-Oxazolone, 4-[(3,4-dimethylphenyl)methylene]-2-methyl-, (4Z)-(676626-91-8)
• EPA Substance Registry System: 5(4H)-Oxazolone, 4-[(3,4-dimethylphenyl)methylene]-2-methyl-, (4Z)-(676626-91-8)

Safety Data

• Hazardous Substances Data: 676626-91-8(Hazardous Substances Data)

Upstream product

• 120-14-9 3,4-dimethoxy-benzaldehyde 
• 543-24-8 N-acetylglycine 
• 5973-71-7 3,4-dimethylbenzaldehyde 

Downstream Products

• 1430416-81-1 C₂₆H₂₄O₆ 
• 1403877-52-0 C₃₄H₃₃NO₈ 
• 1430416-97-9 C₂₄H₂₃NO₆ 
• 1430416-99-1 C₂₂H₂₃NO₇ 
• 143815-52-5 (Z)-3-(3,4-dimethoxyphenyl)-2-hydroxyacrylic acid 
• 32255-79-1 2-hydroxy-3-(3,4-dimethoxyphenyl)propanoic acid 
• 1322088-10-7 allyl 3-(3,4-dimethoxyphenyl)-2-hydroxypropanoate 
• 54814-41-4 (+/-)-(R)-methyl 3-(3,4-dimethoxyphenyl)-2-hydroxypropanoate 
• 1403877-22-4 (E)-1-(allyloxy)-3-(3,4-dimethoxyphenyl)-1-oxopropan-2-yl cinnamate 
• 1403877-23-5 (E)-1-(allyloxy)-3-(3,4-dimethoxyphenyl)-1-oxopropan-2-yl 3-p-tolylacrylate 
• 1403877-24-6 C₂₄H₂₃F₃O₆ 
• 1403877-19-9 (E)-1-(allyloxy)-3-(3,4-dimethoxyphenyl)-1-oxopropan-2-yl 3-(4-fluorophenyl)acrylate 
• 1430417-21-2 (E)-1-(allyloxy)-3-(3,4-dimethoxyphenyl)-1-oxopropan-2-yl 3-(2,3-dihydrobenzofuran-6-yl)acrylate 
• 1430417-23-4 (E)-1-(allyloxy)-3-(3,4-dimethoxyphenyl)-1-oxopropan-2-yl 3-(3,4-bis(tert-butyldimethylsilyloxy)phenyl)acrylate 

Relevant articles and documents

Synthesis of derivatives of methyl rosmarinate and their inhibitory activities against matrix metalloproteinase-1 (MMP-1)

A series of MMP-1 inhibitors have been identified based upon a methyl rosmarinate scaffold using structure-based drug design methods. The best compound in the series showed an IC50 value of 0.4 μM. A docking study was conducted for compound (S)

Potent, selective tetrahydro-β-carboline antagonists of the serotonin 2B (5HT(2B)) contractile receptor in the rat stomach fundus

A series of potent, selective 5HT(2B) receptor antagonists has been identified based upon yohimbine, with SAR studies resulting in a 1000-fold increase in 5HT(2B) receptor affinity relative to the starting structure (- log K(B)s > 10.0 have been obtained). These high-affinity tetrahydro-β- carboline antagonists are able to discriminate among the 5HT2 family of serotonin receptors, with members of the series showing selectivities of more than 100-fold versus both the 5HT(2A) and 5HT(2C) receptors based upon radioligand binding and functional assays. As the first compounds reported with such selectivity and enhanced receptor affinity, these tetrahydro-β- carboline antagonists are useful tools for elucidating the role of serotonin acting at the 5HT(2B) receptor in normal and disease physiology.