67673-42-1

Basic information

• Product Name: 1-[4-(1H-pyrazol-1-yl)phenyl]-1H-pyrazole
• Synonyms: 1-[4-(1H-pyrazol-1-yl)phenyl]-1H-pyrazole
• CAS NO: 67673-42-1
• Molecular Weight: 210.238
• Mol File: 67673-42-1.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 1-[4-(1H-pyrazol-1-yl)phenyl]-1H-pyrazole(CAS DataBase Reference)
• NIST Chemistry Reference: 1-[4-(1H-pyrazol-1-yl)phenyl]-1H-pyrazole(67673-42-1)
• EPA Substance Registry System: 1-[4-(1H-pyrazol-1-yl)phenyl]-1H-pyrazole(67673-42-1)

Safety Data

• Hazardous Substances Data: 67673-42-1(Hazardous Substances Data)

Upstream product

• 288-13-1 NH-pyrazole 
• 106-39-8 bromochlorobenzene 
• 624-38-4 para-diiodobenzene 
• 589-87-7 1,4-bromoiodobenzene 
• 106-37-6 1.4-dibromobenzene 
• 13788-92-6 1-(4-bromophenyl)-1H-pyrazole 

Downstream Products

• 1314002-61-3 1,1'-(2-iodophenylene)-1,4-bis(5-iodo-1H-pyrazole) 
• 67673-45-4 2,2',5,5'-Tetra(1-pyrazolyl)biphenyl 
• 67673-44-3 C₁₂H₈Li₂N₄ 
• 67673-43-2 C₁₂H₉LiN₄ 
• 67673-47-6 1,1'-Bis<4-(1-pyrazolyl)phenyl>-5,5'-bipyrazol 
• 67673-46-5 8,11:20,23-Diethenotetrapyrazolo<1,5-a:5',1'-c:1'',5''-i:5''',1'''-k><1,4,9,12>tetraazacyclohexadecin 

Relevant articles and documents

L -(-) -Quebrachitol as a Ligand for Selective Copper(0)-Catalyzed N-Arylation of Nitrogen-Containing Heterocycles

l-(-)-Quebrachitol (QCT) has been found as a ligand of copper powder for selective N-arylation of nitrogen-containing heterocycles with aryl halides. Furthermore, another potential catalytic system (copper powder/QCT/t-BuOK) was successfully adapted to unactivated aryl chlorides.

N-aryl pyrazoles: DFT calculations of CH acidity and deprotonative metallation using a combination of lithium and zinc amides

A series of N-aryl and N-heteroaryl pyrazoles have been deproto-metallated using a 2,2,6,6-tetramethylpiperidino-based mixed lithium-zinc combination. Mono-, di-, and tri-iodides have been obtained after subsequent trapping with iodine, depending on the s

Mild conditions for copper-catalysed N-arylation of pyrazoles

Copper-catalysed N-arylation of pyrazoles with aryl or heteroaryl bromides or iodides, which can include functional substituents, was performed under the mildest conditions yet described, with excellent yields and selectivity, by the use as catalyst of a combination of cuprous oxide with a set of inexpensive, chelating oxime-type ligands not previously known to promote such reactions. Other original bi-, tri- or tetradentate ligands providing nitrogen and/or oxygen as chelating atoms were also successfully tested in this type of arylation. ( Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004).