67720-42-7

Basic information

• Product Name: 2-Amino-3,5-dicyano-6-hydroxy-4-phenylpyridine
• Synonyms: 6-AMINO-1,2-DIHYDRO-2-OXO-4-PHENYLPYRIDINE-3,5-DICARBONITRILE;2-Amino-3,5-dicyano-6-hydroxy-4-phenylpyridine
• CAS NO: 67720-42-7
• Molecular Formula: C₁₃H₈N₄O
• Molecular Weight: 236.23
• Mol File: 67720-42-7.mol
• Article Data: 6

Chemical Properties

• Melting Point: >300 °C(Solv: ethanol (64-17-5); N,N-dimethylformamide (68-12-2))
• Boiling Point: 414.6±45.0 °C(Predicted)
• Appearance: /
• Density: 1.40±0.1 g/cm3(Predicted)
• PKA: 3.50±0.10(Predicted)
• CAS DataBase Reference: 2-Amino-3,5-dicyano-6-hydroxy-4-phenylpyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Amino-3,5-dicyano-6-hydroxy-4-phenylpyridine(67720-42-7)
• EPA Substance Registry System: 2-Amino-3,5-dicyano-6-hydroxy-4-phenylpyridine(67720-42-7)

Safety Data

• Hazardous Substances Data: 67720-42-7(Hazardous Substances Data)

Usage

Chemical compound

2-Amino-3,5-dicyano-6-hydroxy-4-phenylpyridine

Molecular weight

248.23 g/mol

Type

Heterocyclic organic compound

Family

Pyridine family

Functional groups

Amino group (NH2), cyano group (CN), hydroxyl group (OH), and phenyl group

Biological activities

Anticancer, antiparasitic, antiviral

Potential use

Developing new drugs for various diseases

Research target

Medicinal and pharmaceutical research.

Upstream product

• 79388-04-8 1,6-diamino-2-oxo-4-phenyl-1,2-dihydropyridine-3,5-dicarbonitrile 
• 100-52-7 benzaldehyde 
• 109-77-3 malononitrile 
• 2700-22-3 Benzylidenemalononitrile 
• 187277-70-9 α-(bromothiocyanatomethyl)benzylidenemalononitrile 
• 107-91-5 cyanoacetic acid amide 
• 79359-40-3 2-amino-4-phenyl-6-phenylsulfanyl-pyridine-3,5-dicarbonitrile 
• 79359-36-7 2-amino-6-(2-amino-phenylsulfanyl)-4-phenyl-pyridine-3,5-dicarbonitrile 
• 96583-92-5 6-amino-2-chloro-4-phenylpyridine-3,5-dicarbonitrile 

Downstream Products

• 96583-92-5 6-amino-2-chloro-4-phenylpyridine-3,5-dicarbonitrile 
• 1086-02-8 2,6-dichloro-4-phenylpyridine-3,5-dicarbonitrile 
• 157139-76-9 ethyl 3,5-diamino-4-phenyldithieno<3',2'-e:2,3-b>pyridine-2,6-dicarboxylate 
• 157139-77-0 ethyl 3,5-di(pyrrol-1-yl)-4-phenyldithieno<3',2'-e:2,3-b>pyridine-2,6-dicarboxylate 
• 157139-78-1 4-phenyl-2,6-di(pyrrolidine-1-carbonyl)-3,5-di(pyrrol-1-yl)dithieno<3',2'-e:2,3-b>pyridine 
• 1589009-78-8 3-methyl-6-oxo-8-phenyl-1,3,4,6-tetrahydro-2H-pyrido[1,2-a][1,3,5]triazine-7,9-dicarbonitrile 
• 1589009-79-9 3-benzyl-6-oxo-8-phenyl-1,3,4,6-tetrahydro-2H-pyrido[1,2-a][1,3,5]triazine-7,9-dicarbonitrile 
• 1589009-81-3 3-(4-methylphenyl)-6-oxo-8-phenyl-1,3,4,6-tetrahydro-2H-pyrido[1,2-a][1,3,5]triazine-7,9-dicarbonitrile 
• 1589009-82-4 3-(4-fluorophenyl)-6-oxo-8-phenyl-1,3,4,6-tetrahydro-2H-pyrido[1,2-a][1,3,5]triazine-7,9-dicarbonitrile 
• 1589009-77-7 3,3'-(1,4-phenylene)bis(6-oxo-8-phenyl-1,3,4,6-tetrahydro-2H-pyrido[1,2-a][1,3,5]triazine-7,9-dicarbonitrile) 

Relevant articles and documents

Synthesis of pyrido[1,2-a][1,3,5]triazine derivatives by aminomethylation of 6-amino-4-aryl-2-oxo-1,2-dihydropyridine-3,5-dicarbonitriles

The aminomethylation of 6-amino-4-aryl-2-oxo-1,2-dihydropyridine-3,5- dicarbonitriles by treatment with primary amines and an excess of formaldehyde resulted in the formation of 3-R-8-aryl-6-oxo-1,3,4,6-tetrahydro-2H-pyrido[1,2- a][1,3,5]triazine-7,9-dica

An efficient and greener approach to the synthesis of 3,5-dicyanopyridin- 2(1H)-one derivatives in aqueous media under microwave irradiation conditions

(Chemical Equation Presented) A facile and greener synthesis of a series of 3,5-dicyanopyridin-2(1H)-one derivatives was accomplished via the one-pot reaction of aldehyde, malononitrile and sodium hydroxide in aqueous media under microwave irradiation. Th

A Convenient Synthesis of N-Amino-2-pyridones

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